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JCGG-STR008276 JCGG-STR029533
β1,4-N-acetylgalactosaminyltransferase-IV (B4GALNT4) transfers GalNAc from UDP-GalNAc to GlcNAcβ-R, synthesizing N,N'-diacetyllactosamine, GalNAcβ1→4GlcNAc (LacdiNAc) on N- and O-glycans. B4GALNT4 is also known as B4GalNac-T4 and NGalNAc-T1. Both B4GALNT3 and B4GALNT4 can synthesize LacdiNAc structures, which occur on various glycoproteins including lutropin (LH), thyrotropin (TSH), zona pellucida 3 (ZP3), and extracellular matrix glycoproteins. Expression patterns of two glycosyltransferases are different each other.

N-Acetylgalactosaminyltransferase

GGDB SymbolB4GALNT4
Alias FLJ25045, NGalNAc-T1, Beta4GalNAc-T4    details
Designationbeta 1,4 N-acetylgalactosaminyltransferase 4
OrganismHomo sapiens
GeneID 338707
HGNC 26315
mRNA NM_178537       (CDS)
Protein NP_848632       (CDS)
map11p15.5
EC#
CAZy
OMIM
This page does not indicate all of the enzymatic reaction, and expression of "B4GALNT4".