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JCGG-STR025633 JCGG-STR025667
ALG1 encodes beta-1,4-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. GDP-mannose and chitobiosyldiphosphodolichol are used as donor and acceptor substrates, respectively. ALG1 complements the defect of the yeast alg1 mutant. Mutation of ALG1 is associated with congenital disorder of glycosylation type 1K.
congenital disorders of glycosylation lipid-linked oligosaccharide

Mannosyltransferases

GGDB SymbolALG1
Alias HMT1, HMAT1, HMT-1    details
DesignationGDP-Mannose:GlcNAc2-PP-dolichol beta-1,4-mannosyltransferase
OrganismHomo sapiens
GeneID 56052
HGNC 18294
mRNA NM_019109       (CDS)
Protein NP_061982       (CDS)
map16p13.3
EC# 2.4.1.142   
CAZy
OMIM 605907   
This page does not indicate all of the enzymatic reaction, and expression of "ALG1".