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JCGG-STR025667 JCGG-STR002625
JCGG-STR002625 JCGG-STR028882
ALG2 encodes alpha-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. GDP-mannose is used for the donor substrate. ALG2 appears to be involved in transfer of both alpha-1,3- and alpha-1,6-linked mannose. ALG2 complements the defect of the yeast alg2 mutant. Mutation of ALG2 is associated with congenital disorder of glycosylation type 1I.
congenital disorders of glycosylation lipid-linked oligosaccharide


Alias CDGIi, hALPG2, FLJ14511    details
DesignationGDP-Mannose:ManGlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase, GDP-Mannose:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
OrganismHomo sapiens
GeneID 85365
HGNC 23159
mRNA NM_033087       (CDS)
Protein NP_149078       (CDS)
CAZy GT4   
OMIM 607905   
This page does not indicate all of the enzymatic reaction, and expression of "ALG2".