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JCGG-STR002646 JCGG-STR029281
ALG3 encodes alpha-1,3-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Dolichol-phosphate-mannose is used for the donor substrate. ALG3 complements the defect of the yeast alg3 mutant. Mutation of ALG3 is associated with congenital disorder of glycosylation type 1D.
congenital disorders of glycosylation lipid-linked oligosaccharide


Alias CDGS4, Not56, NOT56L, D16Ertd36e    details
DesignationDol-P-Mannose:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
OrganismHomo sapiens
GeneID 10195
HGNC 23056
mRNA NM_005787       (CDS)
Protein NP_005778       (CDS)
CAZy GT58   
OMIM 608750   
This page does not indicate all of the enzymatic reaction, and expression of "ALG3".