ALG3 encodes alpha-1,3-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Dolichol-phosphate-mannose is used for the donor substrate. ALG3 complements the defect of the yeast alg3 mutant. Mutation of ALG3 is associated with congenital disorder of glycosylation type 1D.
congenital disorders of glycosylation
This page does not indicate all of the enzymatic reaction, and expression of "ALG3".