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JCGG-STR002657 JCGG-STR026135
ALG12 encodes alpha-1,6-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Dolichol-phosphate-mannose is used for the donor substrate. ALG12 complements the defect of the yeast alg12 mutant. Mutation of ALG12 is associated with congenital disorder of glycosylation type 1G.
congenital disorders of glycosylation lipid-linked oligosaccharide

Mannosyltransferases

GGDB SymbolALG12
Alias ECM39, hALG12, MGC3136, PP14673, MGC111358    details
DesignationDol-P-Mannose:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
OrganismHomo sapiens
GeneID 79087
HGNC 19358
mRNA NM_024105       (CDS)
Protein NP_077010       (CDS)
map22q13.33
EC# 2.4.1.130   
CAZy GT22   
OMIM 607144   
This page does not indicate all of the enzymatic reaction, and expression of "ALG12".