ALG12 encodes alpha-1,6-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Dolichol-phosphate-mannose is used for the donor substrate. ALG12 complements the defect of the yeast alg12 mutant. Mutation of ALG12 is associated with congenital disorder of glycosylation type 1G.
congenital disorders of glycosylation
This page does not indicate all of the enzymatic reaction, and expression of "ALG12".