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Cer Glc-Cer
UGCG is a UDP-glucose ceramide glucosyltransferase,which transfers glucose to a ceramide, synthesizing a glucosylceramide (GlcCer). UGCG is also knoan as b-glucosyltransferase (GlcT-I) or glucosylceramide synthase (GCS). GlcCer is a key precursor lipid for the synthesis of glycosphingolipids. Lack of UGCG resulted in embryonic lethality,indicating a vital role of glycosphingolipids during development and differentiation.


Alias GCS    details
DesignationUDP-glucose ceramide glucosyltransferase
OrganismHomo sapiens
GeneID 7357
HGNC 12524
mRNA NM_003358       (CDS)
Protein NP_003349       (CDS)
CAZy GT21   
OMIM 602874   
This page does not indicate all of the enzymatic reaction, and expression of "UGCG".