GXYLT1

JCGG-STR031569		JCGG-STR031321

GXYLT1 encodes UDP-xylose: beta-glucoside alpha1,3-xylosyltransferase 1, which has activity to transfer xyloseto the O-linked glucose on the epidermal growth factor (EGF) domain of Notch protein (involved in Xyla1-3Glc-Ser synthesis). In mammals, the O-linked glucose structure consists of trisaccharide (Xyla1-3Xyla1-3Glc-Ser), in which this enzyme transfers the first xylose only, and the second xylose is synthesized by another enzyme (refer to XXYLT1).
EGF (epidermal growth factor) domain O-linked glucose alpha1,3-xylosyltransferase

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN