GXYLT2

JCGG-STR031569		JCGG-STR031321

GXYLT2 encodes (UDP-xylose: beta-glucoside alpha1,3-xylosyltransferase 2), which has activity to transfer xyloseto the O-linked glucose on the epidermal growth factor (EGF) domain of Notch protein (related to Xyla1-3Glc-Ser synthesis). In mammals, the O-linked glucose structure consists of trisaccharide (Xyla1-3Xyla1-3Glc-Ser), but this enzyme transfers the first xylose only, and the second xylose is synthesized by another enzyme (refer to XXYLT1).
EGF(epidermal growth factor) domain O-linked glucose alpha1,3-xylosyltransferase

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN