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dolichol-phosphate dolichol-phosphate-mannose
DPM3 encodes a subunit of dolichyl-phosphate mannosyltransferase. Dolichol-phosphate-mannose is required for the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositol anchor in the endoplasmic reticulum. Dolichyl-phosphate mannosyltransferase consists of three subunits, DPM1, DPM2 and DPM3. GDP-mannose and dolichol-phosphate are used as donor and acceptor substrates, respectively. DPM3 stabilizes the dolichyl-phosphate mannosyltransferase complex. Mutation of DPM3 is associated with congenital disorder of glycosylation type 1O.
congenital disorders of glycosylation dolichol-phosphate-mannose


Alias MGC34275, MGC125904, MGC125905    details
Designationdolichol-phosphate mannosyltransferase polypeptide 3
OrganismHomo sapiens
GeneID 54344
HGNC 3007
mRNA NM_018973       (CDS)
Protein NP_061846       (CDS)
CAZy GT2   
OMIM 605951   
This page does not indicate all of the enzymatic reaction, and expression of "DPM3".