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JCGG-STR008276 JCGG-STR025633
ALG13 encodes the catalytic subunit of UDP-N-acetylglucosamine transferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. ALG13 protein associates with ALG14 protein to form bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation. Co-expression of ALG13 and ALG14 functionally complements the defect of either alg13 or alg14 mutant in yeast. Mutation of ALG13 is associated with congenital disorder of glycosylation type 1s.
congenital disorders of glycosylation lipid-linked oligosaccharide


GGDB SymbolALG13
Alias GLT28D1, MDS031    details
Designationglycosyltransferase 28 domain containing 1
OrganismHomo sapiens
GeneID 79868
HGNC 30881
mRNA NM_018466       (CDS)
Protein NP_060936       (CDS)
OMIM 300776   
This page does not indicate all of the enzymatic reaction, and expression of "ALG13".