GlycoProtDB ID - GPDB0001634


Protein Name Cadherin EGF LAG seven-pass G-type receptor 2
Protein Accession Number A2AEE7
Gene Celsr2
Length 2919
Status
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
1101
1201
1301
1401
1501
1601
1701
1801
1901
2001
2101
2201
2301
2401
2501
2601
2701
2801
2901
MRSRAASAPL PTPLLPLLLL LLLLPPSPLL GDQVGPCRSL GSGGRSSSGA CAPVGWLCPA SASNLWLYTS RCRESGIELT GHLVPHHDGL RVWCPESGAH
IPLPPSSEGC PWSCRLLGIG GHLSPQGTLT LPEEHPCLKA PRLRCQSCKL AQAPGLRAGE GSPEESLGGR RKRNVNTAPQ FQPPSYQATV PENQPAGTSV
ASLRAIDPDE GEAGRLEYTM DALFDSRSNH FFSLDPITGV VTTAEELDRE TKSTHVFRVT AQDHGMPRRS ALATLTILVT DTNDHDPVFE QQEYKESLRE
NLEVGYEVLT VRATDGDAPP NANILYRLLE GAGGSPSDAF EIDPRSGVIR TRGPVDREEV ESYKLTVEAS DQGRDPGPRS STAIVFLSVE DDNDNAPQFS
EKRYVVQVRE DVTPGAPVLR VTASDRDKGS NALVHYSIMS GNARGQFYLD AQTGALDVVS PLDYETTKEY TLRIRAQDGG RPPLSNVSGL VTVQVLDIND
NAPIFVSTPF QATVLESVPL GYLVLHVQAI DADAGDNARL EYSLAGVGHD FPFTINNGTG WISVAAELDR EEVDFYSFGV EARDHGTPAL TASASVSVTI
LDVNDNNPTF TQPEYTVRLN EDAAVGTSVV TVSAVDRDAH SVITYQITSG NTRNRFSITS QSGGGLVSLA LPLDYKLERQ YVLAVTASDG TRQDTAQIVV
NVTDANTHRP VFQSSHYTVN VNEDRPAGTT VVLISATDED TGENARITYF MEDSIPQFRI DADTGAVTTQ AELDYEDQVS YTLAITARDN GIPQKSDTTY
LEILVNDVND NAPQFLRDSY QGSVYEDVPP FTSVLQISAT DRDSGLNGRV FYTFQGGDDG DGDFIVESTS GIVRTLRRLD RENVAQYVLR AYAVDKGMPP
ARTPMEVTVT VLDVNDNPPV FEQDEFDVFV EENSPIGLAV ARVTATDPDE GTNAQIMYQI VEGNIPEVFQ LDIFSGELTA LVDLDYEDRP EYVLVIQATS
APLVSRATVH VRLLDRNDNP PVLGNFEILF NNYVTNRSSS FPGGAIGRVP AHDPDISDSL TYSFERGNEL SLVLLNASTG ELRLSRALDN NRPLEAIMSV
LVSDGVHSVT AQCSLRVTII TDEMLTHSIT LRLEDMSPER FLSPLLGLFI QAVAATLATP PDHVVVFNVQ RDTDAPGGHI LNVSLSVGQP PGPGGGPPFL
PSEDLQERLY LNRSLLTAIS AQRVLPFDDN ICLREPCENY MRCVSVLRFD SSAPFIASSS VLFRPIHPVG GLRCRCPPGF TGDYCETEVD LCYSRPCGPH
GRCRSREGGY TCLCLDGYTG EHCEASTHSG RCTPGVCKNG GTCVNLLVGG FKCDCPSGDF EKPFCQVTTR SFPARSFITF RGLRQRFHFT LALSFATKER
NGLLLYNGRF NEKHDFVALE VIQEQVQLTF SAGESTTTVS PFVPGGVSDG QWHTVQLKYY NKPLLGQTGL PQGPSEQKVA VVSVDGCDTG VALRFGAMLG
NYSCAAQGTQ GGSKKSLDLT GPLLLGGVPD LPESFPVRMR HFVGCMKDLQ VDSRHIDMAD FIANNGTVPG CPTKKIVCDS SICHNGGTCV NQWNAFSCEC
PLGFGGKSCA QEMANPQRFL GSSLVAWHGL SLPISQPWHL SLMFRTRQAD GVLLQAVTRG RSTITLQLRA GHVVLSVEGT GLQASSLRLE PGRANDGDWH
HAQLALGASG GPGHAILSFD YGQQKAEGNL GPRLHGLHLS NITVGGVPGP ASGVARGFRG CLQGVRVSET PEGISSLDPS RGESINVEPG CSWPDPCDSN
PCPTNSYCSN DWDSYSCSCV LGYYGDNCTN VCDLNPCEHQ SVCTRKPNTP HGYICECLPN YLGPYCETRI DQPCPRGWWG HPTCGPCNCD VSKGFDPDCN
KT
SGECHCKE NHYRPPGSPT CLLCDCYPTG SLSRVCDPED GQCPCKPGVI GRQCDRCDNP FAEVTTNGCE VNYDSCPRAI EAGIWWPRTR FGLPAAAPCP
KGSFGTAVRH CDEHRGWLPP NLFNCTSVTF SELKGFAERL QRNESGLDSG RSQRLALLLR NATQHTSGYF GSDVKVAYQL ATRLLAHESA QRGFGLSATQ
DVHFTENLLR VGSALLDAAN KRHWELIQQT EGGTAWLLQH YEAYASALAQ NMRHTYLSPF TIVTPNIVIS VVRLDKGNFA GTKLPRYEAL RGERPPDLET
TVILPESVFR EMPSMVRSAG PGEAQETEEL ARRQRRHPEL SQGEAVASVI IYHTLAGLLP HNYDPDKRSL RVPKRPVINT PVVSISVHDD EELLPRALDK
PVTVQFRLLE TEERTKPICV FWNHSILVSG TGGWSARGCE VVFRNESHVS CQCNHMTSFA VLMDMSRREN GEILPLKTLT YVALGVTLAA LMLTFLFLTL
LRALRSNQHG IRRNLTAALG LAQLVFLLGI NQADLPFACT VIAILLHFLY LCTFSWALLE ALHLYRALTE VRDVNASPMR FYYMLGWGVP AFITGLAVGL
DPEGYGNPDF CWLSVYDTLI WSFAGPVAFA VSMSVFLYIL SARASCAAQR QGFEKKGPVS GLRSSFTVLL LLSATWLLAL LSVNSDTLLF HYLFAACNCV
QGPFIFLSYV VLSKEVRKAL KFACSRKPSP DPALTTKSTL TSSYNCPSPY ADGRLYQPYG DSAGSLHSAS RSGKSQPSYI PFLLREESTL NPGQVPPGLG
DPSGLFLEGQ AQQHDPDTDS DSDLSLEDDQ SGSYASTHSS DSEEEEEEAA FPGEQGWDSL LGPGAERLPL HSTPKDGGPG SGKVPWLGDF GTTTKENSGS
GPLEERPREN GDALTREGSL GPLPGPSTQP HKGILKKKCL PTISEKSSLL RLPLEQGTGS SRGSSISEGS RHGPPPRPPP RQSLQEQLNG VMPVAMSIKA
GTVDEDSSGS EFLFFNFLH

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
486 NVS
557 NGT
701 NVT
1036 NRS
1076 NAS
1182 NVS
1212 NRS
1230 NIC
1501 NYS 1495 - 1515
FGAMLGNYSCAAQGTQGGSKK
Shared ( 4 )
1565 NGT 1555 - 1575
HIDMADFIANNGTVPGCPTKK
Shared ( 4 )
1741 NIT 1734 - 1756
LHGLHLSNITVGGVPGPASGVAR
Shared ( 4 )
1827 NCT
1830 NVC
1900 NKT
1967 NGC
2024 NCT
2043 NES 2040 - 2051
LQRNESGLDSGR
Shared ( 5 )
2061 NAT
2323 NHS
2345 NES
2414 NLT
2475 NAS
Brain Kidney Kidney(Fut9 KO)
ConA ConA AAL(+)
     
     
     
     
     
     
     
     
   
 
   
     
     
     
     
     
   
     
     
     
     
     
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882
Kaji H, Yamauchi Y, Takahashi N, Isobe T Mass spectrometric identification of N-linked glycopeptides using lectin-mediated affinity capture and glycosylation site--specific stable isotope tagging Nat Protocols 2007;1(6):3019-3027 PMID:17406563

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05