GlycoProtDB ID - GPDB0001667


Protein Name ATP-binding cassette sub-family A member 2
Protein Accession Number A2AJ26
Gene Abca2
Length 2433
Status
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
1101
1201
1301
1401
1501
1601
1701
1801
1901
2001
2101
2201
2301
2401
MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLH
RVVEEGNLFD PVRPSLGSEL EALRQRLEAL SSGPGTWESH SARPAVSSFS LDSVARDQRE LWRFLMQNLS LPNSTAQALL AARVDPSEVY RLLFGPLPDL
DGKLGFLRKQ EPWSRLGSNP LLQMEELLLA PALLEQLTCA PGSGELGRIL TMPEGHQVDL QGYRDAVCSG QATARAQRFS DLAAELRNQL DTAKIAQQLG
FDVPNGSDPQ PQAPSPQSLP ALLGDLLDAQ KLLQDVDVLS ALALLLPQGA CAGQASAPQA SSLNGLANST GIGANSGSNT TVEEGTQSPV SPASPDTLQG
QCSAFVQLWA GLQPILCGNN RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPVGSEADR VILKANETFA FVGNVTHYAQ VWLNISTEIR
SFLEQGRLQQ HLQWLQQYVA DLQLHPEAMN LSLEELPPAL RQDFSLPNGT ALLQQLDTID NAACGWIQFM SKVSVDIFKG FPDEESIVNY TLNQAYQDNV
T
VFASVIFQT RKDGSLPPHV HYKIRQNSSF TEKTNEIRRA YWRPGPNTGG RFYFLYGFVW IQDMMERAII NTFVGHDVVE PGNYVQMFPY PCYTRDDFLF
VIEHMMPLCM VISWVYSVAM TIQHIVAEKE HRLKEVMKTM GLNNAVHWVA WFITGFVQLS ISVTALTAIL KYGQVLMHSH VLIIWLFLAV YAVATIMFCF
LVSVLYSKAK LASACGGIIY FLSYVPYMYV AIREEVAHDK ITAFEKCIAS LMSTTAFGLG SKYFALYEVA GVGIQWHTFS QSPVEGDDFN LLLAVTMLMV
DTVVYGVLTW YIEAVHPGMY GLPRPWYFPL QKSYWLGSGR TEAWEWSWPW AHTPRLSVME EDQACAMESR HFEETRGMEE EPTHLPLVVC VDKLTKVYKN
DKKMALNKLS LNLYENQVVS FLGHNGAGKT TTMSILTGLF PPTSGSATIY GHDIRTEMDE IRKNLGMCPQ HNVLFDRLTV EEHLWFYSRL KSMAQEEIRK
ETDKMIEDLE LSNKRHSLVQ TLSGGMKRKL SVAIAFVGGS RAIILDEPTA GVDPYARRAI WDLILKYKPG RTILLSTHHM DEADLLGDRI AIISHGKLKC
CGSPLFLKGA YGDGYRLTLV KQPAEPGTSQ EPGLASSPSG CPRLSSCSEP QVSQFIRKHV ASSLLVSDTS TELSYILPSE AVKKGAFERL FQQLEHSLDA
LHLSSFGLMD TTLEEVFLKV SEEDQSLENS EADVKESRKD VLPGAEGLTA VGGQAGNLAR CSELAQSQAS LQSASSVGSA RGEEGTGYSD GYGDYRPLFD
NLQDPDNVSL QEAEMEALAQ VGQGSRKLEG WWLKMRQFHG LLVKRFHCAR RNSKALCSQI LLPAFFVCVA MTVALSVPEI GDLPPLVLSP SQYHNYTQPR
GNFIPYANEE RQEYRLRLSP DASPQQLVST FRLPSGVGAT CVLKSPANGS LGPMLNLSSG ESRLLAARFF DSMCLESFTQ GLPLSNFVPP PPSPAPSDSP
VSPDEDSLQA WNMSLPPTAG PETWTSAPSL PRLVHEPVRC TCSAQGTGFS CPSSVGGHPP QMRVVTGDIL TDITGHNVSE YLLFTSDRFR LHRYGAITFG
NVQKSIPASF GARVPPMVRK IAVRRVAQVL YNNKGYHSMP TYLNSLNNAI LRANLPKSKG NPAAYGITVT NHPMNKTSAS LSLDYLLQGT DVVIAIFIIV
AMSFVPASFV VFLVAEKSTK AKHLQFVSGC NPVIYWLANY VWDMLNYLVP ATCCVIILFV FDLPAYTSPT NFPAVLSLFL LYGWSITPIM YPASFWFEVP
SSAYVFLIVI NLFIGITATV ATFLLQLFEH DKDLKVVNSY LKSCFLIFPN YNLGHGLMEM AYNEYINEYY AKIGQFDKMK SPFEWDIVTR GLVAMTVEGF
VGFFLTIMCQ YNFLRQPQRL PVSTKPVEDD VDVASERQRV LRGDADNDMV KIENLTKVYK SRKIGRILAV DRLCLGVRPG ECFGLLGVNG AGKTSTFKML
TGDESTTGGE AFVNGHSVLK DLLQVQQSLG YCPQFDALFD ELTAREHLQL YTRLRGIPWK DEAQVVKWAL EKLELTKYAD KPAGTYSGGN KRKLSTAIAL
IGYPAFIFLD EPTTGMDPKA RRFLWNLILD LIKTGRSVVL TSHSMEECEA LCTRLAIMVN GRLRCLGSIQ HLKNRFGDGY MITVRTKSSQ NVKDVVRFFN
RNFPEAMLKE RHHTKVQYQL KSEHISLAQV FSKMEQVVGV LGIEDYSVSQ TTLDNVFVNF AKKQSDNVEQ QEAEPSSLPS PLGLLSLLRP RPAPTELRAL
VADEPEDLDT EDEGLISFEE ERAQLSFNTD TLC

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
14 NVT
89 NST
168 NLS 164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
173 NST 164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
305 NGS
368 NST
379 NTT
420 NRT
432 NMS 431 - 441
GNMSSLGFTSK
Shared ( 2 )
476 NET
484 NVT
494 NIS
530 NLS
548 NGT
589 NYT
599 NVT
627 NSS 624 - 633
IRQNSSFTEK
Shared ( 2 )
1407 NVS
1495 NYT
1548 NGS 1545 - 1563
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1545 - 1563
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1556 NLS 1545 - 1563
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1545 - 1563
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1612 NMS
1677 NVS
1775 NKT 1760 - 1776
GNPAAYGITVTNHPMNK
Shared ( 3 )
1758 - 1776
SKGNPAAYGITVTNHPMNK
Shared ( 3 )
2054 NLT
Brain Heart Kidney Kidney(Fut9 KO) Kidney(Fut9 WT) Liver Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Skeletal_muscle Stomach Testis
AAL ConA RCA120 ConA AAL AAL(+) AAL(+) RCA120 RCA120 RCA120 ConA ConA AAL
                         
                         
         
   
                   
         
   
                   
                         
                         
                         
                         
 
                     
                         
                         
                         
                         
                         
                         
                         
 
                     
                         
                         
   
 
 
 
   
             
   
 
 
 
   
             
                         
                         
                     
 
 
                     
                         
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882
Kaji H, Yamauchi Y, Takahashi N, Isobe T Mass spectrometric identification of N-linked glycopeptides using lectin-mediated affinity capture and glycosylation site--specific stable isotope tagging Nat Protocols 2007;1(6):3019-3027 PMID:17406563

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05