GlycoProtDB ID - GPDB0003321


Protein Name Angiotensin-converting enzyme
Protein Accession Number P09470
Gene Ace
Length 1312
Status
Reviewed
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
1101
1201
1301
MGAASGQRGR WPLSPPLLML SLLVLLLQPS PAPALDPGLQ PGNFSPDEAG AQLFAESYNS SAEVVMFQST VASWAHDTNI TEENARRQEE AALVSQEFAE
VWGKKAKELY ESIWQNFTDS KLRRIIGSIR TLGPANLPLA QRQQYNSLLS NMSRIYSTGK VCFPNKTATC WSLDPELTNI LASSRSYAKL LFAWEGWHDA
VGIPLKPLYQ DFTAISNEAY RQDDFSDTGA FWRSWYESPS FEESLEHIYH QLEPLYLNLH AYVRRALHRR YGDKYVNLRG PIPAHLLGDM WAQSWENIYD
MVVPFPDKPN LDVTSTMVQK GWNATHMFRV SEEFFTSLGL SPMPPEFWAE SMLEKPTDGR EVVCHASAWD FYNRKDFRIK QCTRVTMEQL ATVHHEMGHV
QYYLQYKDLH VSLRRGANPG FHEAIGDVLA LSVSTPAHLH KIGLLDHVTN DIESDINYLL KMALEKIAFL PFGYLVDQWR WGVFSGRTPP SRYNFDWWYL
RTKYQGICPP VARNETHFDA GAKFHIPNVT PYIRYFVSFV LQFQFHQALC KEAGHQGPLH QCDIYQSAQA GAKLKQVLQA GCSRPWQEVL KDLVGSDALD
AKALLEYFQP VSQWLEEQNQ RNGEVLGWPE NQWRPPLPDN YPEGIDLETD EAKADRFVEE YDRTAQVLLN EYAEANWQYN TNITIEGSKI LLEKSTEVSN
HT
LKYGTRAK TFDVSNFQNS SIKRIIKKLQ NLDRAVLPPK ELEEYNQILL DMETTYSLSN ICYTNGTCMP LEPDLTNMMA TSRKYEELLW AWKSWRDKVG
RAILPFFPKY VEFSNKIAKL NGYTDAGDSW RSLYESDNLE QDLEKLYQEL QPLYLNLHAY VRRSLHRHYG SEYINLDGPI PAHLLGNMWA QTWSNIYDLV
APFPSAPNID ATEAMIKQGW TPRRIFKEAD NFFTSLGLLP VPPEFWNKSM LEKPTDGREV VCHPSAWDFY NGKDFRIKQC TSVNMEDLVI AHHEMGHIQY
FMQYKDLPVT FREGANPGFH EAIGDIMALS VSTPKHLYSL NLLSTEGSGY EYDINFLMKM ALDKIAFIPF SYLIDQWRWR VFDGSITKEN YNQEWWSLRL
KYQGLCPPVP RSQGDFDPGS KFHVPANVPY VRYFVSFIIQ FQFHEALCRA AGHTGPLHKC DIYQSKEAGK LLADAMKLGY SKPWPEAMKL ITGQPNMSAS
AMMNYFKPLT EWLVTENRRH GETLGWPEYN WAPNTARAEG STAESNRVNF LGLYLEPQQA RVGQWVLLFL GVALLVATVG LAHRLYNIRN HHSLRRPHRG
PQFGSEVELR HS

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
43 NFS
59 NSS
79 NIT
116 NFT 108 - 121
ELYESIWQNFTDSK
Shared ( 4 )
151 NMS 143 - 154
QQYNSLLSNMSR
Shared ( 4 )
143 - 154
QQYNSLLSNMSR
Shared ( 4 )
143 - 154
QQYNSLLSNMSR
Shared ( 4 )
165 NKT 161 - 185
VCFPNKTATCWSLDPELTNILASSR
Shared ( 4 )
323 NAT 321 - 329
GWNATHMFR
Shared ( 6 )
321 - 329
GWNATHMFR
Shared ( 6 )
514 NET 504 - 523
YQGICPPVARNETHFDAGAK
Shared ( 6 )
514 - 523
NETHFDAGAK
Shared ( 6 )
528 NVT
682 NIT
700 NHT 695 - 704
STEVSNHTLK
Shared ( 7 )
695 - 708
STEVSNHTLKYGTR
Shared ( 7 )
719 NSS 709 - 723
AKTFDVSNFQNSSIK
Shared ( 7 )
711 - 724
TFDVSNFQNSSIKR
Shared ( 7 )
711 - 723
TFDVSNFQNSSIK
Shared ( 7 )
709 - 724
AKTFDVSNFQNSSIKR
Shared ( 7 )
760 NIC
765 NGT
947 NKS 928 - 948
EADNFFTSLGLLPVPPEFWNK
Shared ( 7 )
1196 NMS 1190 - 1218
LITGQPNMSASAMMNYFKPLTEWLVTENR
Shared ( 8 )
Brain Colon Heart Kidney Kidney(Fut9 KO) Kidney(Fut9 WT) Liver Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Lung Serum Skeletal_muscle Stomach Testis
ConA RCA120 Amide80 Amide80 ConA RCA120 AAL ConA RCA120 AAL(+) AAL(+) ConA RCA120 RCA120 RCA120 AAL ConA RCA120 Amide80 Amide80 ConA RCA120 RCA120 AAL ConA RCA120
                                                   
                                                   
                                                   
           
   
       
 
           
 
 
 
 
 
 
   
   
       
 
       
             
     
           
                             
         
     
     
           
           
 
           
             
         
     
   
 
     
   
                                       
         
   
       
         
                 
                                                   
                                                   
         
 
     
           
         
                                       
             
                                   
       
   
     
         
     
   
       
             
                                   
             
                                                   
                                                   
     
         
                 
           
             
                                   
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882
Kaji H, Yamauchi Y, Takahashi N, Isobe T Mass spectrometric identification of N-linked glycopeptides using lectin-mediated affinity capture and glycosylation site--specific stable isotope tagging Nat Protocols 2007;1(6):3019-3027 PMID:17406563

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05