GlycoProtDB ID - GPDB0003615


Protein Name ATP-binding cassette sub-family A member 2
Protein Accession Number P41234
Gene Abca2
Length 2434
Status
Reviewed
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
1101
1201
1301
1401
1501
1601
1701
1801
1901
2001
2101
2201
2301
2401
MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLH
RVVEEGNLFD PVRPSLGSEL EALRQRLEAL SSGPGTWESH SARPAVSSFS LDSVARDQRE LWRFLMQNLS LPNSTAQALL AARVDPSEVY RLLFGPLPDL
DGKLGFLRKQ EPWSRLGSNP LLQMEELLLA PALLEQLTCA PGSGELGRIL TMPEGHQVDL QGYRDAVCSG QATARAQRFS DLAAELRNQL DTAKIAQQLG
FDVPNGSDPQ PQAPSPQSLP ALLGDLLDAQ KLLQDVDVLS ALALLLPQGA CAGQASAPQA SSLNGLANST GIGANSGSNT TVEEGTQSPV SPASPDTLQG
QCSAFVQLWA GLQPILCGNN RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPVGSEADR VILKANETFA FVGNVTHYAQ VWLNISTEIR
SFLEQGRLQQ HLQWLQQYVA DLQLHPEAMN LSLEELPPAL RQDFSLPNGT ALLQQLDTID NAACGWIQFM SKVSVDIFKG FPDEESIVNY TLNQAYQDNV
T
VFASVIFQT RKDGSLPPHV HYKIRQNSSF TEKTNEIRRA YWRPGPNTGG RFYFLYGLRL DQDMMERAII NTFVGHDVVE PGNYVQMFPY PCYTRDDFLF
VIEHMMPLCM VISWVYSVAM TIQHIVAEKE HRLKEVMKTM GLNNAVHWVA WFITGFVQLS ISVTALTAIL KYCQVLMHSH VLIIWLFLAV YAVATIMFCF
LVSVLYSKAK LASACGGIIY FLSYVPYMYV AIREEVAHDK ITAFEKCIAS RCPQQPLAWV PSTLHCMKWQ EWASIQWHTF SQSPVEGDDF NLLLAVTMLM
VDTVVYGVLT WYIEAVHPGM YGLPRPWYSR YRSPIGWAVG GQKPGSGAGH GHTHRASALW RRIQACAMES RHFEETRGME EEPTHLPLVV CVDKLTKVYK
NDKKLALNKL SLNLYENQVV SFLGHNGAGK TTTMSILTGL FPPTSGSATI YGHDIRTEMD EIRKNLGMCP QHNVLFDRLT VEEHLWFYSR LKSMAQEEIR
KETDKMIEDL ELSNKRHSLV QTLSGGMKRK LSVAIAFVGG SRAIILDEPT AGVDPYARRA IWDLILKYKP GRTILLSTHH MDEADLLGDR IAIISHGKLK
CCGSPLFLKG AYGDGYRLTL VKQPAEPGTS QEPGLASSPS GCPRLSSCSE PQVSQFIRKH VASSLLVSDT STELSYILPS EAVKKGAFER LFQQLEHSLD
ALHLSSFGLM DTTLEEVFLK VSEEDQSLEN SEADVKESRK DVLPGAEGLT AVGGQAGNLA RCSELAQSQA SLQSASSVGS ARGEEGTGYS DGYGDYRPLF
DNLQDPDNVS LQEAEMEALA QVGQGSRKLE GWWLKMRQFH GLLVKRFHCA RRNSKALCSQ ILLPAFFVCV AMTVALSVPE IGDLPPLVLS PSQYHNYTQP
RGNFIPYANE ERQEYRLRLS PDASPQQLVS TFRLPSGVGA TCVLKSPANG SLGPMLNLSS GESRLLAARF FDSMCLESFT QGLPLSNFVP PPPSPAPSDS
PVSPDEDSLQ AWNMSLPPTA GPETWTSAPS LPRLVHEPVR CTCSAQGTGF SCPSSVGGHP PQMRVVTGDI LTDITGHNVS EYLLFTSDRF RLHRYGAITF
GNVQKSIPAS FGARVPPMVR KIAVRRVAQV LYNNKGYHSM PTYLNSLNNA ILRANLPKSK GNPAAYGITV TNHPMNKTSA SLSLDYLLQG TDVVIAIFII
VAMSFVPASF VVFLVAEKST KAKHLQFVSG CNPVIYWLAN YVWDMLNYLV PATCCVIILF VFDLPAYTSP TNFPAVLSLF LLYGWSITPI MYPASFWFEV
PSSAYVFLIV INLFIGITAT VATFLLQLFE HDKDLKVVNS YLKSCFLIFP NYNLGHGLME MAYNEYINEY YAKIGQFDKM KSPFEWDIVT RGLVAMTVEG
FVGFFLTIMC QYNFLRQPQR LPVSTKPVED DVDVASERQR VLRGDADNDM VKIENLTKVY KSRKIGRILA VDRLCLGVRP GECFGLLGVN GAGKTSTFKM
LTGDESTTGG EAFVNGHSVL KDLLQVQQSL GYCPQFDALF DELTAREHLQ LYTRLRGIPW KDEAQVVKWA LEKLELTKYA DKPAGTYSGG NKRKLSTAIA
LIGYPAFIFL DEPTTGMDPK ARRFLWNLIL DLIKTGRSVV LTSHSMEECE ALCTRLAIMV NGRLRCLGSI QHLKNRFGDG YMITVRTKSS QNVKDVVRFF
NRNFPEAMLK ERHHTKVQYQ LKSEHISLAQ VFSKMEQVVG VLGIEDYSVS QTTLDNVFVN FAKKQSDNVE QQEAEPSSLP SPLGLLSLLR PRPAPTELRA
LVADEPEDLD TEDEGLISFE EERAQLSFNT DTLC

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
14 NVT
89 NST
168 NLS 164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
173 NST 164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
164 - 183
FLMQNLSLPNSTAQALLAAR
Shared ( 2 )
305 NGS
368 NST
379 NTT
420 NRT
432 NMS 431 - 441
GNMSSLGFTSK
Shared ( 2 )
476 NET
484 NVT
494 NIS
530 NLS
548 NGT
589 NYT
599 NVT
627 NSS 624 - 633
IRQNSSFTEK
Shared ( 2 )
1408 NVS
1496 NYT
1549 NGS 1546 - 1564
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1546 - 1564
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1557 NLS 1546 - 1564
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1546 - 1564
SPANGSLGPMLNLSSGESR
Shared ( 3 )
1613 NMS
1678 NVS
1776 NKT 1761 - 1777
GNPAAYGITVTNHPMNK
Shared ( 3 )
1759 - 1777
SKGNPAAYGITVTNHPMNK
Shared ( 3 )
2055 NLT
Brain Heart Kidney Kidney(Fut9 KO) Kidney(Fut9 WT) Liver Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Skeletal_muscle Stomach Testis
AAL ConA RCA120 ConA AAL AAL(+) AAL(+) RCA120 RCA120 RCA120 ConA ConA AAL
                         
                         
         
   
                   
         
   
                   
                         
                         
                         
                         
 
                     
                         
                         
                         
                         
                         
                         
                         
 
                     
                         
                         
   
 
 
 
   
             
   
 
 
 
   
             
                         
                         
                     
 
 
                     
                         
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882
Kaji H, Yamauchi Y, Takahashi N, Isobe T Mass spectrometric identification of N-linked glycopeptides using lectin-mediated affinity capture and glycosylation site--specific stable isotope tagging Nat Protocols 2007;1(6):3019-3027 PMID:17406563

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05