GlycoProtDB ID - GPDB0004300


Protein Name Alpha-mannosidase
Protein Accession Number Q3TND6
Gene Man2b2
Length 1018
Status
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
MGPLRWLPLL GQLLLLWPRA AQPAGPIRAF VVPHSHMDVG WVFTVQESMR AYAANVYTTV VAELVRGGQR RFIAVEQEFF RLWWDGVASE QQKQQVRQLL
HEGRLEFVLG GQVMHDEAVT HLDDQILQLT EGHGFLYETF GIRPQFSWHV DPFGASATTP TLFALAGFNA HLISRIDYDL KDAMQEAQML QFVWHGSPSL
SGQQEIFTHV MDHYSYCTPS HIPFSNRSGF YWNGVAVFPE PPPDGVYPNM SEPVTGANIH LYAEALVANV KQRAAWFRTP HVLWPWGCDK QFFNASVQFD
NMDPLLDYIN QRTAQFGISV QYATLNDYFQ ALHATNMTWG IRDHQDFLPY SSEPLQAWTG FCTSRSTLKG LARQASALLY AGESMFTRYM WPDPSGTLDP
TWALQQLQQL RWAVSEVQHH DAITGTESPK VKNMYTEHLR MGMLGVRKLM VSIALGGPPG SGTGAPKDIM GPQVTPVLSV DTRPVGYSAS VYNPLAWKIT
TIITLTVAFP NVSVTDELGH PVSTQIQNST KDPSAYDLLI LTTIPGLNYR HYQVMHARGD QAGTRELVAP RANTLKFSLK LRNQPSQEGK RLVPVMNDCY
ILLFDQDTNM LHSIQDRQSN RTVRMTQEFL EYQANWDVKQ GPISDNYLFA PNNTAEPSWE AVGMEMVAGT LVTDIRQYFY RYITDQEYIY SIHTRLAHPS
LAGELLCQRI EQQYRVGPLD LNREAILRTS SDLNSQQVLY SDNNGYQMQR RPYKAFKSNP IPRNYYPMVQ SAFIEDDKSR LVLLAERPHG VSSQGNGQVE
VMLHRRLWNN LAWDLKYNLT LNDTSIVHPV LWLMLGPKST MTALHPRSGV ALQHGPVVLL KELADEETPV HGPHNPWPVT LPPNLHLQIL SVPGWTYSRS
HAQHLRNLQR GHPEKPQANL QRVLLRLRHL YEAGEDPVLS RPATVDLKVV LRGLGSVVAV EERSLTGTWD VQMLQRWHWS TKTDHLKGHP TSPPRPPGGS
IITVYPKEIR TFFIKFQQ

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
226 NRS
249 NMS
294 NAS
336 NMT
511 NVS
528 NST
597 NDC
620 NRT
652 NNT
818 NLT 817 - 838
YNLTLNDTSIVHPVLWLMLGPK
Shared ( 3 )
822 NDT 817 - 838
YNLTLNDTSIVHPVLWLMLGPK
Shared ( 3 )
Colon Kidney(Fut9 WT) Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Skeletal_muscle Stomach
ConA RCA120 AAL(+) RCA120 RCA120 ConA ConA
             
             
             
             
             
             
             
             
             
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05