GlycoProtDB ID - GPDB0005427


Protein Name CD98 heavy chain
Protein Accession Number Q60849
Gene Slc3a2
Length 532
Status
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
MSQDTEVDMK DVELNELEPE KQPMNAADGA AMSLAGAEKN GLVKIKVAED ETEAGVAAKF TGLSKEELLK VAGSPGWVRT RWALLLLFWL GWLGMLAGAV
VIIVRAPRCR ELPVQRWWHK GALYRIGDLQ AFVGRDAGGI AGLKSHLEYL STLKVKGLVL GPIHKNQKDE INETDLKQIN PTLGSQEDFK DLLQSAKKKS
IHIILDLTPN YQGQNAWFLP AQADIVATKM KEALSSWLQD GVDGFQFRDV GKLMNAPLYL AEWQNITKNL SEDRLVIAGT ESSDLQQIVN ILDSTSDLLL
TSSYLSNSTH TGERTESLDT RLVSATGSHW CSWSVSQAAL LADFIPDHLL RLYQLLLFTL PGTPVFSYGD ELGLQGALPG QPAKAPLMPW NESSIFHIPR
PVSLNMTVKG QNEDPGSLLT QFRRLSDLRG KERSLLHGDF HALSSTPDLF SYIRHWDQNE RYLVVLNFRD SGRSARLGAS NLPAGISLPA SAKLLLSTDS
ARQSREEDTS LKLENLSLNP YEGLLLQFPF VA

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
172 NET 166 - 177
NQKDEINETDLK
Shared ( 8 )
169 - 177
DEINETDLK
Shared ( 8 )
265 NIT 249 - 274
DVGKLMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
253 - 274
LMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
253 - 268
LMNAPLYLAEWQNITK
Shared ( 8 )
253 - 274
LMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
253 - 268
LMNAPLYLAEWQNITK
Shared ( 8 )
260 - 268
LAEWQNITK
Shared ( 8 )
269 NLS 249 - 274
DVGKLMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
253 - 274
LMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
253 - 274
LMNAPLYLAEWQNITKNLSEDR
Shared ( 8 )
307 NST
391 NES 385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
405 NMT 385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
385 - 409
APLMPWNESSIFHIPRPVSLNMTVK
Shared ( 7 )
397 - 409
HIPRPVSLNMTVK
Shared ( 7 )
515 NLS
Brain Colon Heart Kidney Kidney(Fut9 KO) Kidney(Fut9 WT) Liver Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Lung Skeletal_muscle Stomach Testis
AAL ConA RCA120 Amide80 ConA RCA120 Amide80 ConA RCA120 AAL ConA RCA120 AAL(+) AAL(+) AAL RCA120 RCA120 RCA120 RCA120 Amide80 ConA RCA120 Amide80 ConA RCA120 ConA RCA120
                       
                         
                       
                         
                 
                                 
               
       
                       
         
     
 
 
                 
                                 
   
 
   
 
     
 
 
 
                         
                         
                 
                                 
               
       
                       
                 
                                 
                                                     
       
   
     
     
   
   
     
               
                           
                         
           
           
                 
 
     
 
       
   
     
     
   
   
     
               
                           
                         
           
           
                 
 
     
 
                         
                         
                                                     
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882
Kaji H, Yamauchi Y, Takahashi N, Isobe T Mass spectrometric identification of N-linked glycopeptides using lectin-mediated affinity capture and glycosylation site--specific stable isotope tagging Nat Protocols 2007;1(6):3019-3027 PMID:17406563

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05