GlycoProtDB ID - GPDB0005950


Protein Name Alpha-4 integrin
Protein Accession Number Q792F9
Gene Itga4
Length 1032
Status
release : 2016-12-05

Glycosylation Sites

Schema of N-glycosylation site(s) of the protein

Sequence

(__:Potential Sequon , N:Identified Site)

1
101
201
301
401
501
601
701
801
901
1001
MAAEARCRPR SRGIALREAV MLLLYFGVPT GHSYNLDPEN ALLYQGPSGT LFGYSVVLHS HGSKRWLIVG APTASWLSNA SVVNPGAIYR CGIRKNPNQT
CEQLQLGSPS GEPCGKTCLE ERDNQWLGVT LSRQPGENGS IVTCGHRWKN IFYMKSDNKL PTGICYVMPS DLRTELSKRM APCYKDYTRK FGENFASCQA
GISSFYTQDL IVMGAPGSSY WTGTVFVYNI TTNQYKAFVD RQNQVKFGSY LGYSVGAGHF RSPHTTEVVG GAPQHEQIGK AYIFSIDENE LNIVYEMKGK
KLGSYFGASV CAVDLNADGF SDLLVGAPMQ STIREEGRVF VYINSGMGAV MVEMERVLVG SDKYAARFGE SIANLGDIDN DGFEDIAIGA PQEDDLRGAV
YIYNGRVDGI SSTYSQRIEG QQISKSLRMF GQSISGQIDA DNNGYVDVAV GAFQSDSAVL LRTRPVVIVE ASLSHPESVN RTKFDCTENG LPSVCMHLTL
CFSYKGKEVP GYIVLFYNVS LDVHRKAESP SRFYFFSNGT SDVITGSIRV SSSGEKCRTH QAFMRKDVRD ILTPIHVEAT YHLGHHVITK RNTEEFPPLQ
PILQQKKEKD VIRKMINFAR FCAYENCSAD LQVSAKVGFL KPYENKTYLA VGSMKTIMLN VSLFNAGDDA YETTLNVQLP TGLYFIKILD LEEKQINCEV
TESSGIVKLA CSLGYIYVDR LSRIDISFLL DVSSLSRAHE DLSISVHASC ENEGELDQVR DNRVTLTIPL RYEVMLTVHG LVNPTSFVYG SSEENEPETC
MAEKLNLTFH VINTGISMAP NVSVKIMVPN SFLPQDDKLF NVLDVQTTTG QCHFKHYGRE CTFAQQKGIA GTLTDIVKFL SKTDKRLLYC MKADQHCLDF
LCNFGKMESG KEASVHIQLE GRPSILEMDE TSSLKFEIKA TAFPEPHPKV IELNKDENVA HVFLEGLHHQ RPKRHFTIII ITISLLLGLI VLLLISCVMW
KAGFFKRQYK SILQEENRRD SWSYVNSKSN DD

N-glycosylation sites

Potential sites Identified Peptide*1
Position Sequon Position Sequence Unique or Shared
79 NAS
98 NQT 96 - 116
NPNQTCEQLQLGSPSGEPCGK
Shared ( 6 )
138 NGS 134 - 147
QPGENGSIVTCGHR
Shared ( 8 )
229 NIT
480 NRT 463 - 481
TRPVVIVEASLSHPESVNR
Shared ( 6 )
463 - 483
TRPVVIVEASLSHPESVNRTK
Shared ( 6 )
518 NVS
538 NGT 533 - 549
FYFFSNGTSDVITGSIR
Shared ( 5 )
626 NCS
645 NKT
660 NVS
806 NLT 805 - 825
LNLTFHVINTGISMAPNVSVK
Shared ( 4 )
821 NVS 805 - 825
LNLTFHVINTGISMAPNVSVK
Shared ( 4 )
Colon Kidney(Fut9 KO) Kidney(Fut9 WT) Liver: b4GalT-I(+/+) Liver: b4GalT-I(-/-) Skeletal_muscle Stomach
Amide80 AAL(+) AAL(+) RCA120 RCA120 Amide80 ConA Amide80 RCA120
                 
               
           
   
                 
 
   
     
           
 
                 
     
         
                 
                 
                 
     
     
     
     
*1:   _:Potential Sequon     :Asn (glycosylated)     :Gln (deaminated:pyroGlu)     :Met (oxidized)     :Cys (carbamidomethylated and deaminated)

External Links

Publications

Noro E, Togayachi A, Sato T, Tomioka A, Fujita M, Sukegawa M, Suzuki N, Kaji H, Narimatsu H Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice. J Proteome Res 2015;14(9):3823-34 PMID:26244810
Sugahara D, Kaji H, Sugihara K, Asano M, Narimatsu H Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approach Sci Rep 2012;2(): PMID:23002422
Kaji H, Shikanai T, Sasaki-Sawa A, et al Large-scale Identification of N-Glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB J Proteome Res 2012;11(9):4553-4566 PMID:22823882

Entry information

Entry version 2016-12-05
protein sequence version 2016-12-05
Entry status Latest version
Entry history

create : 2016-12-05