| Lectin ID | LfDB0017 |
Molecular Structure
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|---|---|---|---|---|---|
| Lectin Name | E-selectin (CD62E) | ||||
| Pfam Family |
Lectin_C (Lectin C-type domain) |
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| Monosaccharide Specificity | Gal | ||||
| Common Name (Scientific Name) | Human ( Homo sapiens ) | ||||
| Japanese Name [Family] | ヒト [ヒト科] | ||||
| Kingdom | Animal | ||||
| Organ | Endothelium | ||||
| Number of CRD | 1 | ||||
| 3D-fold | others | ||||
| External Link |
GenBank:
AF540378
M61893
M24736
AL021940
M30640
PDB: 1G1T 1ESL Pfam: PF00059 LfDB RDF version: LfDB0017 |
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| Sequence |
1 WSYNTSTEAM TYDEASAYCQ QRYTHLVAIQ NKEEIEYLNS ILSYSPSYYW
51 IGIRKVNNVW VWVGTQKPLT EEAKNWAPGE PNNRQKDEDC VEIYIKREKD 101 VGMWNDERCS KKKLALCYTA ACTNTSCSGH GECVETINNY TCKCDPGFSG 151 LKCEQIV |
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| Reference |
|---|
| Graves BJ Nature 1994, (367)532-8 Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains. [7509040] |
| Somers WS Cell 1994, (103)467-79 Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. [11081633] |
| Li SH J Bioll Chem 1994, (269)4431-7 Consensus repeat domains of E-selectin enhance ligand binding. [7508442] |