Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (traditional nomenclature)
            • Defects in glycolipid synthesis
              • Defects in GPI-anchor biosynthesis
                • Glycosylphosphatidylinositol deficiency [PIGM]
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in glycosphingolipid and glycosylphosphatidylinositol anchor glycosylation
                • Disorders of glycosylphosphatidylinositol anchor biosynthesis
                  • PIGM-CDG [PIGM]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Cardiovascular Diseases
                • Vascular Diseases
                  • Embolism and Thrombosis
                    • Thrombosis
                      • Venous Thrombosis
                        • PIGM-CDG [PIGM]
              • Digestive System Diseases
                • Liver Diseases
                  • Hepatomegaly
                    • PIGM-CDG [PIGM]
                  • Hypertension, Portal
                    • PIGM-CDG [PIGM]
              • Hemic and Lymphatic Diseases
                • Lymphatic Diseases
                  • Splenic Diseases
                    • PIGM-CDG [PIGM]
              • Nervous System Diseases
                • Neurologic Manifestations
                  • Seizures
                    • PIGM-CDG [PIGM]