Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in protein N-glycosylation
                • Defects in lipid-linked oligosaccharide biosynthesis
                  • ALG11-CDG [ALG11]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Digestive System Diseases
                • Gastrointestinal Diseases
                  • Gastrointestinal Hemorrhage
                    • ALG11-CDG [ALG11]
              • Eye Diseases
                • Ocular Motility Disorders
                  • Strabismus
                    • ALG11-CDG [ALG11]
                • Vision Disorders
                  • Vision, Low
                    • ALG11-CDG [ALG11]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Spinal Diseases
                    • Spinal Curvatures
                      • Scoliosis
                        • ALG11-CDG [ALG11]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Microcephaly
                      • ALG11-CDG [ALG11]
                    • ALG11-CDG [ALG11]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Epilepsy
                      • ALG11-CDG [ALG11]
                • Nervous System Malformations
                  • Malformations of Cortical Development
                    • Microcephaly
                      • ALG11-CDG [ALG11]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Psychomotor Disorders
                      • ALG11-CDG [ALG11]
                    • Intellectual Disability
                      • ALG11-CDG [ALG11]
                  • Neuromuscular Manifestations
                    • Muscle Hypotonia
                      • ALG11-CDG [ALG11]
                  • Sensation Disorders
                    • Vision Disorders
                      • Vision, Low
                        • ALG11-CDG [ALG11]
                  • Seizures
                    • ALG11-CDG [ALG11]
                • Cranial Nerve Diseases
                  • Ocular Motility Disorders
                    • Strabismus
                      • ALG11-CDG [ALG11]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Hearing Disorders
                    • Hearing Loss
                      • ALG11-CDG [ALG11]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Hemorrhage
                    • Gastrointestinal Hemorrhage
                      • ALG11-CDG [ALG11]
                • Signs and Symptoms
                  • Body Temperature Changes
                    • ALG11-CDG [ALG11]
                  • Signs and Symptoms, Digestive
                    • Vomiting
                      • ALG11-CDG [ALG11]
                  • Failure to Thrive
                    • ALG11-CDG [ALG11]
              • Skin and Connective Tissue Diseases
                • Skin Diseases
                  • Skin Abnormalities
                    • ALG11-CDG [ALG11]
                  • Skin Diseases, Genetic
                    • ALG11-CDG [ALG11]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • ALG11-CDG [ALG11]
                  • Feeding and Eating Disorders of Childhood
                    • ALG11-CDG [ALG11]
                  • Intellectual Disability
                    • ALG11-CDG [ALG11]