Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Lysosomal Storage Diseases (degradation)
        • Pathogenesis
          • Genetic disorders of glycan degradation
            • Disorders of glycoprotein metabolism
              • Defects in post-translational modification of lysosomal enzymes
                • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
        • Hereditary disorders by systems
          • Genetic disorders of glycan degradation (by systems, signs and symptoms)
            • Diseases
              • Cardiovascular Diseases
                • Heart Diseases
                  • Heart Valve Diseases
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Dysostoses
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Bone Diseases, Metabolic
                    • Mucolipidoses
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Spinal Diseases
                    • Spinal Curvatures
                      • Kyphosis
                        • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Joint Diseases
                  • Contracture
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Hip Dislocation, Congenital
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Limb Deformities, Congenital
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Brain Diseases, Metabolic
                      • Brain Diseases, Metabolic, Inborn
                        • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Communication Disorders
                      • Language Disorders
                        • Speech Disorders
                          • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                    • Intellectual Disability
                      • Mental Retardation, X-Linked
                        • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Neuromuscular Manifestations
                    • Muscle Hypotonia
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Sensation Disorders
                    • Hearing Disorders
                      • Hearing Loss
                        • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Otitis
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Hearing Disorders
                    • Hearing Loss
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Pathological Conditions, Signs and Symptoms
                • Pathological Conditions, Anatomical
                  • Hernia
                    • Hernia, Abdominal
                      • Hernia, Inguinal
                        • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                      • Hernia, Ventral
                        • Hernia, Umbilical
                          • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Signs and Symptoms
                  • Mobility Limitation
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Respiratory Tract Diseases
                • Respiration Disorders
                  • Hoarseness
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Respiratory Insufficiency
                    • Airway Obstruction
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Respiratory Tract Infections
                  • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Stomatognathic Diseases
                • Mouth Diseases
                  • Periodontal Diseases
                    • Gingival Diseases
                      • Gingival Overgrowth
                        • Gingival Hyperplasia
                          • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Motor Skills Disorders
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]