Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Respiratory Tract Diseases
                • Lung Diseases
                  • ALG8-CDG (GDGDB) [ALG8]
                  • Muscular dystrophy, limb-girdle, type 2I (GDGDB) [FKRP]
                  • TMEM165-CDG [TMEM165]
                • Respiration Disorders
                  • Apnea
                    • GCS1-CDG (GDGDB) [GCS1]
                  • Dyspnea
                    • ALG8-CDG (GDGDB) [ALG8]
                    • PGM1-CDG [PGM1]
                  • Respiratory Insufficiency
                    • Hypoventilation
                      • GCS1-CDG (GDGDB) [GCS1]
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                    • ALG1-CDG (GDGDB) [ALG1]
                    • GCS1-CDG (GDGDB) [GCS1]
                    • Fukuyama congenital muscular dystrophy (GDGDB) [FKTN]
                    • Muscular dystrophy, congenital, type 1C (GDGDB) [FKRP]
                    • Muscular dystrophy, limb-girdle, type 2I (GDGDB) [FKRP]
                    • Diastrophic dysplasia [SLC26A2]
                    • Achondrogenesis type IB [SLC26A2]
                    • Neonatal osseous dysplasia I [SLC26A2]
                  • MPDU1-CDG (GDGDB) [MPDU1]
                  • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Respiratory Tract Infections
                  • ALG12-CDG (GDGDB) [ALG12]
                  • DOLK-CDG [TMEM15]
                  • MGAT2-CDG (GDGDB) [MGAT2]
                  • SLC35C1-CDG (GDGDB) [SLC35C1]
                  • SLC35A1-CDG [SLC35A1]
                  • COG4-CDG [COG4]
                  • Fukuyama congenital muscular dystrophy (GDGDB) [FKTN]
                  • ALG13-CDG [ALG13]
                  • COG6-CDG [COG6]
                • Respiratory Hypersensitivity
                  • Asthma
                    • ALG9-CDG (GDGDB) [ALG9]
                • Ehlers-Danlos syndrome, musculocontractural type [CHST14]
      • Lysosomal Storage Diseases (degradation)
        • Hereditary disorders by systems
          • Genetic disorders of glycan degradation (by systems, signs and symptoms)
            • Diseases
              • Respiratory Tract Diseases
                • Lung Diseases
                  • Hurler syndrome (GDGDB) [IDUA]
                  • Hurler-Scheie syndrome (GDGDB) [IDUA]
                  • Scheie syndrome (GDGDB) [IDUA]
                  • Gaucher disease, type I (GDGDB) [GBA]
                  • Gaucher disease, type II (GDGDB) [GBA]
                  • Gaucher disease, type III (GDGDB) [GBA]
                  • Niemann-Pick disease, type A (GDGDB) [SMPD1]
                  • Niemann-Pick disease, type B (GDGDB) [SMPD1]
                  • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
                  • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
                  • Farber Lipogranulomatosis (GDGDB) [ASAH1]
                    • Farber Lipogranulomatosis, type 1 [ASAH1]
                    • Farber Lipogranulomatosis, type 4 [ASAH1]
                  • Pompe disease (GDGDB) [GAA]
                • Respiration Disorders
                  • Apnea
                    • Sleep Apnea Syndromes
                      • Sleep Apnea, Obstructive
                        • Hurler syndrome (GDGDB) [IDUA]
                        • Hurler-Scheie syndrome (GDGDB) [IDUA]
                        • Scheie syndrome (GDGDB) [IDUA]
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                        • Morquio syndrome A (GDGDB) [GALNS]
                        • Morquio syndrome B (GDGDB) [GLB1]
                        • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
                        • Mucopolysaccharidosis VII (GDGDB) [GUSB]
                  • Dyspnea
                    • Gaucher disease, type II (GDGDB) [GBA]
                    • Krabbe disease (GDGDB) [GALC]
                      • Krabbe disease, infantile form [GALC]
                    • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
                    • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
                    • Farber Lipogranulomatosis (GDGDB) [ASAH1]
                    • Pompe disease (GDGDB) [GAA]
                  • Hoarseness
                    • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                    • Hurler syndrome (GDGDB) [IDUA]
                    • Hurler-Scheie syndrome (GDGDB) [IDUA]
                    • Scheie syndrome (GDGDB) [IDUA]
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                    • Farber Lipogranulomatosis (GDGDB) [ASAH1]
                  • Respiratory Insufficiency
                    • Airway Obstruction
                      • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                      • Hurler syndrome (GDGDB) [IDUA]
                      • Hurler-Scheie syndrome (GDGDB) [IDUA]
                      • Scheie syndrome (GDGDB) [IDUA]
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                      • Morquio syndrome A (GDGDB) [GALNS]
                      • Morquio syndrome B (GDGDB) [GLB1]
                      • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
                      • Mucopolysaccharidosis VII (GDGDB) [GUSB]
                    • Krabbe disease (GDGDB) [GALC]
                      • Krabbe disease, infantile form [GALC]
                    • Combined saposin deficiency (GDGDB) [PSAP]
                    • Pompe disease (GDGDB) [GAA]
                • Respiratory Tract Infections
                  • Aspartylglucosaminuria (GDGDB) [AGA]
                  • Fucosidosis (GDGDB) [FUCA1]
                  • Alpha-mannosidosis (GDGDB) [MAN2B1]
                  • Beta-mannosidosis (GDGDB) [MANBA]
                  • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                  • Mucolipidosis III (alpha/beta) (GDGDB) [GNPTAB]
                  • Hurler syndrome (GDGDB) [IDUA]
                  • Hurler-Scheie syndrome (GDGDB) [IDUA]
                  • Scheie syndrome (GDGDB) [IDUA]
                  • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Sanfilippo syndrome A (GDGDB) [SGSH]
                  • Sanfilippo syndrome B (GDGDB) [NAGLU]
                  • Sanfilippo syndrome C (GDGDB) [HGSNAT]
                  • Sanfilippo syndrome D (GDGDB) [GNS]
                  • Morquio syndrome A (GDGDB) [GALNS]
                  • Morquio syndrome B (GDGDB) [GLB1]
                  • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
                  • Mucopolysaccharidosis VII (GDGDB) [GUSB]
                  • Niemann-Pick disease, type A (GDGDB) [SMPD1]
                  • Niemann-Pick disease, type B (GDGDB) [SMPD1]
                  • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
                  • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
                  • Combined saposin deficiency (GDGDB) [PSAP]
                  • Pompe disease (GDGDB) [GAA]