Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Lysosomal Storage Diseases (degradation)
        • Pathogenesis
          • Genetic disorders of glycan degradation
            • Disorders of glycosaminoglycan metabolism
              • Mucopolysaccharidosis II (GDGDB) [IDS]
        • Hereditary disorders by systems
          • Genetic disorders of glycan degradation (by systems, signs and symptoms)
            • Diseases
              • Cardiovascular Diseases
                • Cardiovascular Abnormalities
                  • Heart Defects, Congenital
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Heart Diseases
                  • Cardiomegaly
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Heart Failure
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Heart Valve Diseases
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Myocardial Ischemia
                    • Coronary Disease
                      • Coronary Artery Disease
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Vascular Diseases
                  • Peripheral Vascular Diseases
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Myocardial Ischemia
                    • Coronary Disease
                      • Coronary Artery Disease
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Digestive System Diseases
                • Liver Diseases
                  • Hepatomegaly
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Eye Diseases
                • Retinal Diseases
                  • Retinal Degeneration
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Hemic and Lymphatic Diseases
                • Lymphatic Diseases
                  • Splenic Diseases
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Dwarfism
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                    • Dysostoses
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Spinal Diseases
                    • Spinal Stenosis
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Joint Diseases
                  • Contracture
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Macrocephaly
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Intracranial Hypertension
                      • Hydrocephalus
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Spinal Cord Diseases
                    • Spinal Cord Compression
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Demyelinating Diseases
                  • Hereditary Central Nervous System Demyelinating Diseases
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Nervous System Malformations
                  • Malformations of Cortical Development
                    • Macrocephaly
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Neuromuscular Diseases
                  • Peripheral Nervous System Diseases
                    • Mononeuropathies
                      • Median Neuropathy
                        • Carpal Tunnel Syndrome
                          • Mucopolysaccharidosis II (GDGDB) [IDS]
                    • Nerve Compression Syndromes
                      • Carpal Tunnel Syndrome
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Neurologic Manifestations
                  • Sensation Disorders
                    • Hearing Disorders
                      • Hearing Loss
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                    • Vision Disorders
                      • Vision, Low
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Otitis
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Hearing Disorders
                    • Hearing Loss
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Pathological Conditions, Signs and Symptoms
                • Pathological Conditions, Anatomical
                  • Hernia
                    • Hernia, Abdominal
                      • Hernia, Inguinal
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                      • Hernia, Ventral
                        • Hernia, Umbilical
                          • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Signs and Symptoms
                  • Mobility Limitation
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Respiratory Tract Diseases
                • Respiration Disorders
                  • Apnea
                    • Sleep Apnea Syndromes
                      • Sleep Apnea, Obstructive
                        • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Hoarseness
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
                  • Respiratory Insufficiency
                    • Airway Obstruction
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
                • Respiratory Tract Infections
                  • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Skin and Connective Tissue Diseases
                • Connective Tissue Diseases
                  • Mucinoses
                    • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Stomatognathic Diseases
                • Mouth Diseases
                  • Tongue Diseases
                    • Macroglossia
                      • Mucopolysaccharidosis II (GDGDB) [IDS]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • Mucopolysaccharidosis II (GDGDB) [IDS]