Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Lysosomal Storage Diseases (degradation)
        • Pathogenesis
          • Genetic disorders of glycan degradation
            • Disorders of sphingolipid metabolism and other lipid storage disorders
              • Sphingolipidosis
                • Other sphingolipidosis
                  • Sulfatidosis
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]
        • Hereditary disorders by systems
          • Genetic disorders of glycan degradation (by systems, signs and symptoms)
            • Diseases
              • Digestive System Diseases
                • Liver Diseases
                  • Hepatomegaly
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Hemic and Lymphatic Diseases
                • Lymphatic Diseases
                  • Splenic Diseases
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Spinal Diseases
                    • Spinal Curvatures
                      • Kyphosis
                        • Multiple sulfatase deficiency (GDGDB) [SUMF1]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • Multiple sulfatase deficiency (GDGDB) [SUMF1]
                  • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Brain Diseases, Metabolic
                      • Brain Diseases, Metabolic, Inborn
                        • Multiple sulfatase deficiency (GDGDB) [SUMF1]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Communication Disorders
                      • Language Disorders
                        • Speech Disorders
                          • Multiple sulfatase deficiency (GDGDB) [SUMF1]
                  • Sensation Disorders
                    • Hearing Disorders
                      • Hearing Loss
                        • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Hearing Disorders
                    • Hearing Loss
                      • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Pathological Conditions, Signs and Symptoms
                • Signs and Symptoms
                  • Mobility Limitation
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Skin and Connective Tissue Diseases
                • Skin Diseases
                  • Skin Abnormalities
                    • Ichthyosis
                      • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Stomatognathic Diseases
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • Multiple sulfatase deficiency (GDGDB) [SUMF1]