Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (traditional nomenclature)
            • Defects in N-glycan biosynthesis
              • Disorders of N-linked glycosylation - Congenital disorders of glycosylation (CDGs)
                • Type I CDGs
                  • CDG-If (GDGDB) [MPDU1]
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in multiple glycosylation and other pathways
                • MPDU1-CDG (GDGDB) [MPDU1]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Eye Diseases
                • Vision Disorders
                  • Vision, Low
                    • MPDU1-CDG (GDGDB) [MPDU1]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Dwarfism
                      • MPDU1-CDG (GDGDB) [MPDU1]
              • Nervous System Diseases
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Psychomotor Disorders
                      • MPDU1-CDG (GDGDB) [MPDU1]
                  • Neuromuscular Manifestations
                    • Muscle Hypertonia
                      • MPDU1-CDG (GDGDB) [MPDU1]
                  • Sensation Disorders
                    • Vision Disorders
                      • Vision, Low
                        • MPDU1-CDG (GDGDB) [MPDU1]
                  • Seizures
                    • MPDU1-CDG (GDGDB) [MPDU1]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Growth Disorders
                    • MPDU1-CDG (GDGDB) [MPDU1]
                • Signs and Symptoms
                  • Failure to Thrive
                    • MPDU1-CDG (GDGDB) [MPDU1]
              • Respiratory Tract Diseases
                • Respiration Disorders
                  • MPDU1-CDG (GDGDB) [MPDU1]
              • Skin and Connective Tissue Diseases
                • Skin Diseases
                  • Skin Abnormalities
                    • MPDU1-CDG (GDGDB) [MPDU1]
                  • Dermatitis
                    • Dermatitis, Exfoliative
                      • MPDU1-CDG (GDGDB) [MPDU1]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • MPDU1-CDG (GDGDB) [MPDU1]
                  • Feeding and Eating Disorders of Childhood
                    • MPDU1-CDG (GDGDB) [MPDU1]