Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (traditional nomenclature)
            • Defects in N-glycan biosynthesis
              • Disorders of N-linked glycosylation - Congenital disorders of glycosylation (CDGs)
                • Type I CDGs
                  • CDG-Ij (GDGDB) [DPAGT1]
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in protein N-glycosylation
                • Defects in lipid-linked oligosaccharide biosynthesis
                  • DPAGT1-CDG (GDGDB) [DPAGT1]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Eye Diseases
                • Lens Diseases
                  • Cataract
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Ocular Motility Disorders
                  • Strabismus
                    • Exotropia
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Hemic and Lymphatic Diseases
                • Hematologic Diseases
                  • Anemia
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Blood Protein Disorders
                    • Hypoproteinemia
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Male Urogenital Diseases
                • Urogenital Abnormalities
                  • Cryptorchidism
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Musculoskeletal Diseases
                • Joint Diseases
                  • Contracture
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                      • Jaw Abnormalities
                        • Micrognathism
                          • DPAGT1-CDG (GDGDB) [DPAGT1]
                    • Microcephaly
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Epilepsy
                      • Epilepsy, Generalized
                        • Spasms, Infantile
                          • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Nervous System Malformations
                  • Malformations of Cortical Development
                    • Microcephaly
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Communication Disorders
                      • Language Disorders
                        • Speech Disorders
                          • DPAGT1-CDG (GDGDB) [DPAGT1]
                    • Intellectual Disability
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Neuromuscular Manifestations
                    • Muscle Hypertonia
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                    • Muscle Hypotonia
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Dyskinesias
                    • Tremor
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Seizures
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                • Cranial Nerve Diseases
                  • Ocular Motility Disorders
                    • Strabismus
                      • Exotropia
                        • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Hyperbilirubinemia
                    • Jaundice
                      • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Respiratory Tract Diseases
                • Respiration Disorders
                  • Respiratory Insufficiency
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • DPAGT1-CDG (GDGDB) [DPAGT1]
              • Stomatognathic Diseases
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Jaw Abnormalities
                      • Micrognathism
                        • DPAGT1-CDG (GDGDB) [DPAGT1]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Feeding and Eating Disorders of Childhood
                    • DPAGT1-CDG (GDGDB) [DPAGT1]
                  • Intellectual Disability
                    • DPAGT1-CDG (GDGDB) [DPAGT1]