Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (traditional nomenclature)
            • Defects in N-glycan biosynthesis
              • Disorders of N-linked glycosylation - Congenital disorders of glycosylation (CDGs)
                • Type II CDGs
                  • CDG-IIa (GDGDB) [MGAT2]
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in protein N-glycosylation
                • Defects in N-glycosylation
                  • Defect in N-glycan branching
                    • MGAT2-CDG (GDGDB) [MGAT2]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Endocrine System Diseases
                • Gonadal Disorders
                  • Puberty, Delayed
                    • MGAT2-CDG (GDGDB) [MGAT2]
              • Hemic and Lymphatic Diseases
                • Hematologic Diseases
                  • Blood Coagulation Disorders
                    • MGAT2-CDG (GDGDB) [MGAT2]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Dwarfism
                      • MGAT2-CDG (GDGDB) [MGAT2]
                  • Bone Diseases, Metabolic
                    • Osteoporosis
                      • MGAT2-CDG (GDGDB) [MGAT2]
                  • Spinal Diseases
                    • Spinal Curvatures
                      • MGAT2-CDG (GDGDB) [MGAT2]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • MGAT2-CDG (GDGDB) [MGAT2]
                  • Limb Deformities, Congenital
                    • MGAT2-CDG (GDGDB) [MGAT2]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Epilepsy
                      • MGAT2-CDG (GDGDB) [MGAT2]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Psychomotor Disorders
                      • MGAT2-CDG (GDGDB) [MGAT2]
                  • Neuromuscular Manifestations
                    • Muscular Atrophy
                      • MGAT2-CDG (GDGDB) [MGAT2]
                  • Seizures
                    • MGAT2-CDG (GDGDB) [MGAT2]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Hearing Disorders
                    • Hearing Loss
                      • MGAT2-CDG (GDGDB) [MGAT2]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Growth Disorders
                    • MGAT2-CDG (GDGDB) [MGAT2]
                  • Hemorrhage
                    • MGAT2-CDG (GDGDB) [MGAT2]
                • Signs and Symptoms
                  • Signs and Symptoms, Digestive
                    • Diarrhea
                      • MGAT2-CDG (GDGDB) [MGAT2]
                    • MGAT2-CDG (GDGDB) [MGAT2]
                  • Failure to Thrive
                    • MGAT2-CDG (GDGDB) [MGAT2]
              • Respiratory Tract Diseases
                • Respiratory Tract Infections
                  • MGAT2-CDG (GDGDB) [MGAT2]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • MGAT2-CDG (GDGDB) [MGAT2]
                  • Feeding and Eating Disorders of Childhood
                    • MGAT2-CDG (GDGDB) [MGAT2]