Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (traditional nomenclature)
            • Disorders of O-linked glycosylation
              • Defects in O-galactosyl glycan biosynthesis
                • Bruck syndrome 2 (GDGDB) [PLOD2]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Osteochondrodysplasias
                      • Osteogenesis Imperfecta
                        • Bruck syndrome 2 (GDGDB) [PLOD2]
                  • Bone Diseases, Metabolic
                    • Osteoporosis
                      • Bruck syndrome 2 (GDGDB) [PLOD2]
                • Joint Diseases
                  • Contracture
                    • Bruck syndrome 2 (GDGDB) [PLOD2]
                  • Bruck syndrome 2 (GDGDB) [PLOD2]
                • Musculoskeletal Abnormalities
                  • Limb Deformities, Congenital
                    • Lower Extremity Deformities, Congenital
                      • Foot Deformities, Congenital
                        • Clubfoot
                          • Bruck syndrome 2 (GDGDB) [PLOD2]
                  • Arthrogryposis
                    • Bruck syndrome 2 (GDGDB) [PLOD2]
              • Pathological Conditions, Signs and Symptoms
                • Pathological Conditions, Anatomical
                  • Hernia
                    • Hernia, Abdominal
                      • Hernia, Inguinal
                        • Bruck syndrome 2 (GDGDB) [PLOD2]
              • Skin and Connective Tissue Diseases
                • Connective Tissue Diseases
                  • Collagen Diseases
                    • Osteogenesis Imperfecta
                      • Bruck syndrome 2 (GDGDB) [PLOD2]
              • Wounds and Injuries
                • Fractures, Bone
                  • Fractures, Spontaneous
                    • Bruck syndrome 2 (GDGDB) [PLOD2]