Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in protein N-glycosylation
                • Defects in lipid-linked oligosaccharide biosynthesis
                  • ALG13-CDG [ALG13]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Digestive System Diseases
                • Liver Diseases
                  • Hepatomegaly
                    • ALG13-CDG [ALG13]
              • Eye Diseases
                • Eye Diseases, Hereditary
                  • Optic Atrophies, Hereditary
                    • ALG13-CDG [ALG13]
                • Ocular Motility Disorders
                  • Nystagmus, Pathologic
                    • Nystagmus, Congenital
                      • ALG13-CDG [ALG13]
                • Optic Nerve Diseases
                  • Optic Atrophy
                    • Optic Atrophies, Hereditary
                      • ALG13-CDG [ALG13]
                  • ALG13-CDG [ALG13]
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Spinal Diseases
                    • Spinal Curvatures
                      • Scoliosis
                        • ALG13-CDG [ALG13]
                • Joint Diseases
                  • Contracture
                    • ALG13-CDG [ALG13]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Craniofacial Dysostosis
                      • Hypertelorism
                        • ALG13-CDG [ALG13]
                    • Maxillofacial Abnormalities
                      • Jaw Abnormalities
                        • Micrognathism
                          • ALG13-CDG [ALG13]
                      • ALG13-CDG [ALG13]
                    • Microcephaly
                      • ALG13-CDG [ALG13]
                    • ALG13-CDG [ALG13]
                  • Limb Deformities, Congenital
                    • Lower Extremity Deformities, Congenital
                      • Foot Deformities, Congenital
                        • ALG13-CDG [ALG13]
                    • Upper Extremity Deformities, Congenital
                      • Hand Deformities, Congenital
                        • ALG13-CDG [ALG13]
                    • ALG13-CDG [ALG13]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Intracranial Hypertension
                      • Hydrocephalus
                        • ALG13-CDG [ALG13]
                    • Epilepsy
                      • ALG13-CDG [ALG13]
                    • Hydrocephalus
                      • ALG13-CDG [ALG13]
                • Demyelinating Diseases
                  • Hereditary Central Nervous System Demyelinating Diseases
                    • ALG13-CDG [ALG13]
                • Nervous System Malformations
                  • Malformations of Cortical Development
                    • Microcephaly
                      • ALG13-CDG [ALG13]
                • Neurodegenerative Diseases
                  • Heredodegenerative Disorders, Nervous System
                    • ALG13-CDG [ALG13]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Psychomotor Disorders
                      • ALG13-CDG [ALG13]
                  • Neuromuscular Manifestations
                    • Muscle Hypotonia
                      • ALG13-CDG [ALG13]
                  • Seizures
                    • ALG13-CDG [ALG13]
                • Cranial Nerve Diseases
                  • Ocular Motility Disorders
                    • Nystagmus, Pathologic
                      • Nystagmus, Congenital
                        • ALG13-CDG [ALG13]
                  • Optic Nerve Diseases
                    • Optic Atrophy
                      • Optic Atrophies, Hereditary
                        • ALG13-CDG [ALG13]
                    • ALG13-CDG [ALG13]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Hemorrhage
                    • ALG13-CDG [ALG13]
                • Signs and Symptoms
                  • Edema
                    • ALG13-CDG [ALG13]
              • Respiratory Tract Diseases
                • Respiratory Tract Infections
                  • ALG13-CDG [ALG13]
              • Stomatognathic Diseases
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Jaw Abnormalities
                      • Micrognathism
                        • ALG13-CDG [ALG13]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Feeding and Eating Disorders of Childhood
                    • ALG13-CDG [ALG13]