Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in multiple glycosylation and other pathways
                • Defects in vesicular transport
                  • Defects in COG protein complex
                    • COG6-CDG [COG6]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Digestive System Diseases
                • Gastrointestinal Diseases
                  • COG6-CDG [COG6]
                • Liver Diseases
                  • Hepatomegaly
                    • COG6-CDG [COG6]
                  • Liver Cirrhosis
                    • COG6-CDG [COG6]
                  • COG6-CDG [COG6]
                • Digestive System Abnormalities
                  • COG6-CDG [COG6]
              • Female Urogenital Diseases and Pregnancy Complications
                • Female Urogenital Diseases
                  • Urologic Diseases
                    • Kidney Diseases
                      • Nephrosis
                        • COG6-CDG [COG6]
              • Hemic and Lymphatic Diseases
                • Hematologic Diseases
                  • Blood Coagulation Disorders
                    • COG6-CDG [COG6]
              • Male Urogenital Diseases
                • Urologic Diseases
                  • Kidney Diseases
                    • Nephrosis
                      • COG6-CDG [COG6]
              • Musculoskeletal Diseases
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • COG6-CDG [COG6]
                      • Retrognathia
                        • COG6-CDG [COG6]
                    • Microcephaly
                      • COG6-CDG [COG6]
                  • Limb Deformities, Congenital
                    • COG6-CDG [COG6]
              • Nervous System Diseases
                • Nervous System Malformations
                  • Malformations of Cortical Development
                    • Microcephaly
                      • COG6-CDG [COG6]
                • Neurologic Manifestations
                  • Neuromuscular Manifestations
                    • Muscle Hypotonia
                      • COG6-CDG [COG6]
                  • Seizures
                    • COG6-CDG [COG6]
              • Pathological Conditions, Signs and Symptoms
                • Pathologic Processes
                  • Hemorrhage
                    • COG6-CDG [COG6]
                • Signs and Symptoms
                  • Signs and Symptoms, Digestive
                    • Diarrhea
                      • COG6-CDG [COG6]
                    • Vomiting
                      • COG6-CDG [COG6]
                  • Failure to Thrive
                    • COG6-CDG [COG6]
              • Respiratory Tract Diseases
                • Respiratory Tract Infections
                  • COG6-CDG [COG6]
              • Stomatognathic Diseases
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Jaw Abnormalities
                      • Retrognathia
                        • COG6-CDG [COG6]
              • Immune System Diseases
                • Immunologic Deficiency Syndromes
                  • Dysgammaglobulinemia
                    • COG6-CDG [COG6]
                  • COG6-CDG [COG6]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Developmental Disabilities
                    • COG6-CDG [COG6]