Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Carbohydrate Metabolism, Inborn Errors (synthesis)
        • Pathogenesis
          • Genetic disorders of glycan synthesis (new nomenclature)
            • Congenital disorders of glycosylation (CDGs)
              • Defects in protein N-glycosylation
                • Defects in N-glycosylation
                  • Defects in N-glycan trimming
                    • Mental retardation, autosomal recessive 15 [MAN1B1]
        • Hereditary disorders by systems
          • Genetic disorders of glycan synthesis (by systems, signs and symptoms)
            • Diseases
              • Musculoskeletal Diseases
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Craniofacial Dysostosis
                      • Hypertelorism
                        • Mental retardation, autosomal recessive 15 [MAN1B1]
                    • Maxillofacial Abnormalities
                      • Mental retardation, autosomal recessive 15 [MAN1B1]
                    • Mental retardation, autosomal recessive 15 [MAN1B1]
              • Nervous System Diseases
                • Central Nervous System Diseases
                  • Brain Diseases
                    • Epilepsy
                      • Mental retardation, autosomal recessive 15 [MAN1B1]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Psychomotor Disorders
                      • Mental retardation, autosomal recessive 15 [MAN1B1]
                    • Communication Disorders
                      • Language Disorders
                        • Speech Disorders
                          • Mental retardation, autosomal recessive 15 [MAN1B1]
                    • Intellectual Disability
                      • Mental retardation, autosomal recessive 15 [MAN1B1]
                  • Seizures
                    • Mental retardation, autosomal recessive 15 [MAN1B1]
              • Nutritional and Metabolic Diseases
                • Nutrition Disorders
                  • Overnutrition
                    • Obesity
                      • Mental retardation, autosomal recessive 15 [MAN1B1]
            • Psychiatry and Psychology
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Intellectual Disability
                    • Mental retardation, autosomal recessive 15 [MAN1B1]