Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Mental retardation, autosomal recessive 15'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in protein N-glycosylation
      • Defects in N-glycosylation
        • Defects in N-glycan trimming
          • Mental retardation, autosomal recessive 15 [MAN1B1]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Musculoskeletal Diseases
      • Musculoskeletal Abnormalities
        • Craniofacial Abnormalities
          • Craniofacial Dysostosis
            • Hypertelorism
              • Mental retardation, autosomal recessive 15 [MAN1B1]
          • Maxillofacial Abnormalities
            • Mental retardation, autosomal recessive 15 [MAN1B1]
          • Mental retardation, autosomal recessive 15 [MAN1B1]
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Brain Diseases
          • Epilepsy
            • Mental retardation, autosomal recessive 15 [MAN1B1]
      • Neurologic Manifestations
        • Neurobehavioral Manifestations
          • Psychomotor Disorders
            • Mental retardation, autosomal recessive 15 [MAN1B1]
          • Communication Disorders
            • Language Disorders
              • Speech Disorders
                • Mental retardation, autosomal recessive 15 [MAN1B1]
          • Intellectual Disability
            • Mental retardation, autosomal recessive 15 [MAN1B1]
        • Seizures
          • Mental retardation, autosomal recessive 15 [MAN1B1]
    • Nutritional and Metabolic Diseases
      • Nutrition Disorders
        • Overnutrition
          • Obesity
            • Mental retardation, autosomal recessive 15 [MAN1B1]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Intellectual Disability
          • Mental retardation, autosomal recessive 15 [MAN1B1]