Legend:

• Concept Types
  • target (disease type)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Alpha-mannosidosis, type II (later-onset)'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of glycoprotein metabolism
    • Defects in glycoprotein degradation
      • Mannosidase deficiency diseases
        • Alpha-mannosidosis (GDGDB) [MAN2B1]
          • Alpha-mannosidosis, type II (later-onset) [MAN2B1]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)