Legend:

• Concept Types
  • target (multiple types disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'GM2 gangliosidosis'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of sphingolipid metabolism and other lipid storage disorders
    • Sphingolipidosis
      • Gangliosidosis
        • GM2 gangliosidosis
          • Tay-Sachs disease (GDGDB) [HEXA]
            • Tay-Sachs disease, infantile form [HEXA]
            • Tay-Sachs disease, late-onset forms [HEXA]
          • Sandhoff disease (GDGDB) [HEXB]
            • Sandhoff disease, infantile form [HEXB]
            • Sandhoff disease, juvenile form [HEXB]
            • Sandhoff disease, adult form [HEXB]
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)