Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'GM2-gangliosidosis, AB variant'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of sphingolipid metabolism and other lipid storage disorders
    • Sphingolipidosis
      • Gangliosidosis
        • GM2 gangliosidosis
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Eye Diseases
      • Retinal Diseases
        • Retinal Degeneration
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
    • Musculoskeletal Diseases
      • Muscular Diseases
        • Muscle Weakness
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Brain Diseases
          • Brain Diseases, Metabolic
            • Brain Diseases, Metabolic, Inborn
              • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
      • Neurologic Manifestations
        • Neuromuscular Manifestations
          • Muscle Weakness
            • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
        • Paralysis
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
        • Seizures
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
        • Sensation Disorders
          • Hearing Disorders
            • Hearing Loss
              • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
          • Vision Disorders
            • Blindness
              • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
    • Otorhinolaryngologic Diseases
      • Ear Diseases
        • Hearing Disorders
          • Hearing Loss
            • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
    • Pathological Conditions, Signs and Symptoms
      • Signs and Symptoms
        • Mobility Limitation
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Developmental Disabilities
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
        • Motor Skills Disorders
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]