Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Muscle Hypotonia'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Neuromuscular Manifestations
          • Muscle Hypotonia
            • Beta-mannosidosis (GDGDB) [MANBA]
            • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
            • Combined saposin deficiency (GDGDB) [PSAP]
            • Wolman disease (GDGDB) [LIPA]
            • Pompe disease (GDGDB) [GAA]