Legend:

• Concept Types

'Paraparesis, Spastic'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Paresis
          • Paraparesis
            • Paraparesis, Spastic
              • Metachromatic leukodystrophy (GDGDB) [ARSA]
              • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
              • Niemann-Pick disease, type A (GDGDB) [SMPD1]