Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Spondylocostal dysostosis 3, autosomal recessive' 'LFNG-CDG'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)
  • Disorders of O-linked glycosylation
    • Defects in O-fucosylglycan synthesis
      • Spondylocostal dysostosis 3, autosomal recessive [LFNG]

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in protein O-glycosylation
      • Defects in O-fucosylglycan synthesis
        • LFNG-CDG [LFNG]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Developmental
          • LFNG-CDG [LFNG]
        • Spinal Diseases
          • Spinal Curvatures
            • Scoliosis
              • LFNG-CDG [LFNG]
          • Spondylosis
            • LFNG-CDG [LFNG]
      • Musculoskeletal Abnormalities
        • LFNG-CDG [LFNG]