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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT16 is the 16th member of this enzyme family. This isozyme is identified by Raman et al. in 2012.

GALNACT16 GALNTL1 GalNAc-T16 O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias GALNTL1    details
DesignationUDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
OrganismHomo sapiens
GeneID 57452
HGNC 23233
mRNA NM_020692.2      
Protein NP_065743.2      
CAZy GT27   
OMIM 615132   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT16".