Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

• Congenital, Hereditary, and Neonatal Diseases and Abnormalities related to Glycans
  • Genetic Diseases, Inborn
    • Metabolism, Inborn Errors
      • Lysosomal Storage Diseases (degradation)
        • Pathogenesis
          • Genetic disorders of glycan degradation
            • Disorders of glycoprotein metabolism
              • Defects in glycoprotein degradation
                • Mannosidase deficiency diseases
                  • Beta-mannosidosis (GDGDB) [MANBA]
        • Hereditary disorders by systems
          • Genetic disorders of glycan degradation (by systems, signs and symptoms)
            • Diseases
              • Musculoskeletal Diseases
                • Bone Diseases
                  • Bone Diseases, Developmental
                    • Dysostoses
                      • Beta-mannosidosis (GDGDB) [MANBA]
                • Musculoskeletal Abnormalities
                  • Craniofacial Abnormalities
                    • Maxillofacial Abnormalities
                      • Beta-mannosidosis (GDGDB) [MANBA]
              • Neoplasms
                • Neoplasms by Histologic Type
                  • Neoplasms, Vascular Tissue
                    • Angiokeratoma
                      • Beta-mannosidosis (GDGDB) [MANBA]
              • Nervous System Diseases
                • Neuromuscular Diseases
                  • Peripheral Nervous System Diseases
                    • Beta-mannosidosis (GDGDB) [MANBA]
                • Neurologic Manifestations
                  • Neurobehavioral Manifestations
                    • Communication Disorders
                      • Language Disorders
                        • Speech Disorders
                          • Beta-mannosidosis (GDGDB) [MANBA]
                    • Intellectual Disability
                      • Beta-mannosidosis (GDGDB) [MANBA]
                  • Neuromuscular Manifestations
                    • Muscle Hypotonia
                      • Beta-mannosidosis (GDGDB) [MANBA]
                  • Seizures
                    • Beta-mannosidosis (GDGDB) [MANBA]
                  • Sensation Disorders
                    • Hearing Disorders
                      • Hearing Loss
                        • Beta-mannosidosis (GDGDB) [MANBA]
                    • Somatosensory Disorders
                      • Hypesthesia
                        • Beta-mannosidosis (GDGDB) [MANBA]
              • Otorhinolaryngologic Diseases
                • Ear Diseases
                  • Otitis
                    • Beta-mannosidosis (GDGDB) [MANBA]
                  • Hearing Disorders
                    • Hearing Loss
                      • Beta-mannosidosis (GDGDB) [MANBA]
                • Pharyngeal Diseases
                  • Deglutition Disorders
                    • Beta-mannosidosis (GDGDB) [MANBA]
              • Respiratory Tract Diseases
                • Respiratory Tract Infections
                  • Beta-mannosidosis (GDGDB) [MANBA]
              • Stomatognathic Diseases
                • Stomatognathic System Abnormalities
                  • Maxillofacial Abnormalities
                    • Beta-mannosidosis (GDGDB) [MANBA]
            • Psychiatry and Psychology
              • Behavior and Behavior Mechanisms
                • Behavior
                  • Behavioral Symptoms
                    • Child Reactive Disorders
                      • Beta-mannosidosis (GDGDB) [MANBA]
                    • Depression
                      • Beta-mannosidosis (GDGDB) [MANBA]
                    • Beta-mannosidosis (GDGDB) [MANBA]
              • Mental Disorders
                • Mental Disorders Diagnosed in Childhood
                  • Motor Skills Disorders
                    • Beta-mannosidosis (GDGDB) [MANBA]
                  • Intellectual Disability
                    • Beta-mannosidosis (GDGDB) [MANBA]