Legend:

• Concept Types
  • target (pathway-based classification term)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Disorders of glycosaminoglycan metabolism'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of glycosaminoglycan metabolism
    • Mucopolysaccharidosis I
      • Hurler syndrome (GDGDB) [IDUA]
      • Hurler-Scheie syndrome (GDGDB) [IDUA]
      • Scheie syndrome (GDGDB) [IDUA]
    • Mucopolysaccharidosis II (GDGDB) [IDS]
    • Mucopolysaccharidosis III
      • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Sanfilippo syndrome B (GDGDB) [NAGLU]
      • Sanfilippo syndrome C (GDGDB) [HGSNAT]
      • Sanfilippo syndrome D (GDGDB) [GNS]
    • Mucopolysaccharidosis IV
      • Morquio syndrome A (GDGDB) [GALNS]
      • Morquio syndrome B (GDGDB) [GLB1]
    • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
      • Maroteaux-Lamy syndrome, severe form [ARSB]
      • Maroteaux-Lamy syndrome, mild form [ARSB]
      • Maroteaux-Lamy syndrome, intermediate form [ARSB]
    • Mucopolysaccharidosis VII (GDGDB) [GUSB]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)