Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Sanfilippo syndrome A'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of glycosaminoglycan metabolism
    • Mucopolysaccharidosis III
      • Sanfilippo syndrome A (GDGDB) [SGSH]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Digestive System Diseases
      • Liver Diseases
        • Hepatomegaly
          • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Developmental
          • Dwarfism
            • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Dysostoses
            • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Joint Diseases
        • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Musculoskeletal Abnormalities
        • Craniofacial Abnormalities
          • Macrocephaly
            • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Maxillofacial Abnormalities
            • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Brain Diseases
          • Intracranial Hypertension
            • Hydrocephalus
              • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Movement Disorders
          • Dyskinesias
            • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Demyelinating Diseases
        • Hereditary Central Nervous System Demyelinating Diseases
          • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Nervous System Malformations
        • Malformations of Cortical Development
          • Macrocephaly
            • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Neurologic Manifestations
        • Neurobehavioral Manifestations
          • Communication Disorders
            • Language Disorders
              • Speech Disorders
                • Sanfilippo syndrome A (GDGDB) [SGSH]
            • Learning Disorders
              • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Intellectual Disability
            • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Seizures
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Sensation Disorders
          • Hearing Disorders
            • Hearing Loss
              • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Vision Disorders
            • Vision, Low
              • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Sleep Disorders
        • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Otorhinolaryngologic Diseases
      • Ear Diseases
        • Otitis
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Hearing Disorders
          • Hearing Loss
            • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Pathological Conditions, Signs and Symptoms
      • Pathological Conditions, Anatomical
        • Hernia
          • Hernia, Abdominal
            • Hernia, Inguinal
              • Sanfilippo syndrome A (GDGDB) [SGSH]
            • Hernia, Ventral
              • Hernia, Umbilical
                • Sanfilippo syndrome A (GDGDB) [SGSH]
      • Signs and Symptoms
        • Mobility Limitation
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Signs and Symptoms, Digestive
          • Diarrhea
            • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Neurologic Manifestations
          • Sleep Disorders
            • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Respiratory Tract Diseases
      • Respiratory Tract Infections
        • Sanfilippo syndrome A (GDGDB) [SGSH]
    • Stomatognathic Diseases
      • Stomatognathic System Abnormalities
        • Maxillofacial Abnormalities
          • Sanfilippo syndrome A (GDGDB) [SGSH]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Child Behavior Disorders
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Developmental Disabilities
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Intellectual Disability
          • Sanfilippo syndrome A (GDGDB) [SGSH]
        • Learning Disorders
          • Sanfilippo syndrome A (GDGDB) [SGSH]