Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Muscular Atrophy'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Neuromuscular Manifestations
          • Muscular Atrophy
            • PMM2-CDG (GDGDB) [PMM2]
            • MGAT2-CDG (GDGDB) [MGAT2]
            • POMT1/POMT2-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMT1,POMT2]
            • POMGNT1-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMGNT1]
            • Fukuyama congenital muscular dystrophy (GDGDB) [FKTN]
            • Muscular dystrophy, limb-girdle, type 2M (GDGDB) [FKTN]
            • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
            • Muscular dystrophy, congenital, type 1C (GDGDB) [FKRP]
            • Muscular dystrophy, limb-girdle, type 2I (GDGDB) [FKRP]
            • LARGE-CDG (cong. muscular dystrophy spectrum) [LARGE]
            • Duchenne muscular dystrophy [DMD]
            • Hereditary inclusion body myopathy type 2 [GNE]
            • Nonaka myopathy (GDGDB) [GNE]
            • Ehlers-Danlos syndrome, type VI (GDGDB) (GDGDB) [PLOD1]
            • DPM3-CDG [DPM3]
            • Myasthenia, congenital, with tubular aggregates 1 [GFPT1]