Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Cardiomyopathy, dilated, 1X'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)
  • Disorders of O-linked glycosylation
    • Defects in O-mannose glycans
      • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in protein O-glycosylation
      • Defects in O-mannosylglycan synthesis
        • FKTN-CDG (cong. muscular dystrophy spectrum)
          • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Cardiovascular Diseases
      • Heart Diseases
        • Cardiomegaly
          • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
        • Cardiomyopathies
          • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
        • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
    • Musculoskeletal Diseases
      • Muscular Diseases
        • Muscle Weakness
          • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
        • Muscular Disorders, Atrophic
          • Muscular Dystrophies
            • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
    • Nervous System Diseases
      • Neurologic Manifestations
        • Neuromuscular Manifestations
          • Muscle Hypotonia
            • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
          • Muscular Atrophy
            • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
          • Muscle Weakness
            • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
      • Neuromuscular Diseases
        • Muscular Diseases
          • Muscular Disorders, Atrophic
            • Muscular Dystrophies
              • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]
    • Pathological Conditions, Signs and Symptoms
      • Signs and Symptoms
        • Mobility Limitation
          • Cardiomyopathy, dilated, 1X (GDGDB) [FKTN]