Legend:

• Concept Types
  • target (pathway-based classification term)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Type II CDGs'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)
  • Defects in N-glycan biosynthesis
    • Disorders of N-linked glycosylation - Congenital disorders of glycosylation (CDGs)
      • Type II CDGs
        • CDG-IIa (GDGDB) [MGAT2]
        • CDG-IIb (GDGDB) [GCS1]
        • CDG-IIc (GDGDB) [SLC35C1]
        • CDG-IId (GDGDB) [B4GALT1]
        • CDG-IIe (GDGDB) [COG7]
        • CDG-IIf [SLC35A1]
        • CDG-IIg [COG1]
        • CDG-IIh [COG8]
        • CDG-IIi [COG5]
        • CDG-IIj [COG4]

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)