Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Tn polyagglutination syndrome, somatic (SOMATIC MUTATION)'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)
  • Disorders of O-linked glycosylation
    • Defects in O-GalNAc glycans
      • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in protein O-glycosylation
      • Defects in O-GalNAc glycan biosynthesis
        • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Hemic and Lymphatic Diseases
      • Hematologic Diseases
        • Anemia
          • Anemia, Hemolytic
            • Anemia, Hemolytic, Autoimmune
              • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]
        • Blood Platelet Disorders
          • Thrombocytopenia
            • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]
        • Leukocyte Disorders
          • Leukopenia
            • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]
    • Immune System Diseases
      • Autoimmune Diseases
        • Anemia, Hemolytic, Autoimmune
          • Tn polyagglutination syndrome, somatic (SOMATIC MUTATION) [C1GALT1C1]