Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Bone Diseases, Metabolic'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Metabolic
          • Osteoporosis
            • PMM2-CDG (GDGDB) [PMM2]
            • MGAT2-CDG (GDGDB) [MGAT2]
            • COG1-CDG [COG1]
            • ATP6VOA2-CDG [ATP6V0A2]
            • B4GALT7-CDG [B4GALT7]
            • Bruck syndrome 2 (GDGDB) [PLOD2]
            • Lysyl hydroxylase 3 deficiency (GDGDB) [PLOD3]
            • DDOST-CDG [DDOST]
            • TMEM165-CDG [TMEM165]
            • Multiple joint dislocations, short stature, craniofacial dysmorphism, and congenital heart defects [B3GAT3]