Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'DDOST-CDG'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in protein N-glycosylation
      • Defects in N-glycosylation
        • Defects in oligosaccharyltransferase subunits
          • DDOST-CDG [DDOST]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Digestive System Diseases
      • Liver Diseases
        • DDOST-CDG [DDOST]
    • Eye Diseases
      • Ocular Motility Disorders
        • Strabismus
          • DDOST-CDG [DDOST]
    • Hemic and Lymphatic Diseases
      • Hematologic Diseases
        • Blood Coagulation Disorders
          • Coagulation Protein Disorders
            • DDOST-CDG [DDOST]
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Metabolic
          • Osteoporosis
            • DDOST-CDG [DDOST]
    • Nervous System Diseases
      • Demyelinating Diseases
        • Hereditary Central Nervous System Demyelinating Diseases
          • DDOST-CDG [DDOST]
      • Neurodegenerative Diseases
        • Heredodegenerative Disorders, Nervous System
          • DDOST-CDG [DDOST]
      • Neurologic Manifestations
        • Neurobehavioral Manifestations
          • Psychomotor Disorders
            • DDOST-CDG [DDOST]
          • Communication Disorders
            • Language Disorders
              • Speech Disorders
                • DDOST-CDG [DDOST]
        • Neuromuscular Manifestations
          • Muscle Hypotonia
            • DDOST-CDG [DDOST]
      • Cranial Nerve Diseases
        • Ocular Motility Disorders
          • Strabismus
            • DDOST-CDG [DDOST]
    • Otorhinolaryngologic Diseases
      • Ear Diseases
        • Otitis
          • DDOST-CDG [DDOST]
      • Pharyngeal Diseases
        • Deglutition Disorders
          • DDOST-CDG [DDOST]
    • Pathological Conditions, Signs and Symptoms
      • Signs and Symptoms
        • Signs and Symptoms, Digestive
          • Constipation
            • DDOST-CDG [DDOST]
        • Failure to Thrive
          • DDOST-CDG [DDOST]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Developmental Disabilities
          • DDOST-CDG [DDOST]
        • Motor Skills Disorders
          • DDOST-CDG [DDOST]