Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Ear Diseases'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Otorhinolaryngologic Diseases
      • Ear Diseases
        • Otitis
          • SLC35C1-CDG (GDGDB) [SLC35C1]
          • DDOST-CDG [DDOST]
        • Hearing Disorders
          • Hearing Loss
            • ALG12-CDG (GDGDB) [ALG12]
            • RFT1-CDG [RFT1]
            • MGAT2-CDG (GDGDB) [MGAT2]
            • B3GALTL-CDG [B3GALTL]
            • Lysyl hydroxylase 3 deficiency (GDGDB) [PLOD3]
            • ALG11-CDG [ALG11]
            • Temtamy preaxial brachydactyly syndrome [CHSY1]
            • Spondyloepiphyseal dysplasia with congenital joint dislocations [CHST3]
            • Hyperphosphatasia with mental retardation syndrome 1 [PIGV]