Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Congenital dyserythropoietic anaemia, type II' 'SEC23B-CDG'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)
  • Defects in N-glycan biosynthesis
    • Other disorders that affect N-glycans
      • Congenital dyserythropoietic anaemia, type II (GDGDB) [SEC23B]

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)
  • Congenital disorders of glycosylation (CDGs)
    • Defects in multiple glycosylation and other pathways
      • Defects in vesicular transport
        • SEC23B-CDG (GDGDB) [SEC23B]

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Digestive System Diseases
      • Biliary Tract Diseases
        • Cholelithiasis
          • SEC23B-CDG (GDGDB) [SEC23B]
    • Hemic and Lymphatic Diseases
      • Hematologic Diseases
        • Anemia
          • Anemia, Hemolytic
            • Anemia, Hemolytic, Congenital
              • Anemia, Dyserythropoietic, Congenital
                • SEC23B-CDG (GDGDB) [SEC23B]
          • SEC23B-CDG (GDGDB) [SEC23B]
      • Lymphatic Diseases
        • Splenic Diseases
          • SEC23B-CDG (GDGDB) [SEC23B]
    • Pathological Conditions, Signs and Symptoms
      • Pathologic Processes
        • Hyperbilirubinemia
          • Jaundice
            • SEC23B-CDG (GDGDB) [SEC23B]
      • Signs and Symptoms
        • Reticulocytosis
          • SEC23B-CDG (GDGDB) [SEC23B]